{"title":"营养补充剂（哈拉斯）对吸烟者和非吸烟者体内一氧化碳水平的影响：一项观察研究。","authors":"Vidyadevi Chandavarkar, Mithilesh Narayan Mishra, Deepak Bhargava, Premalatha Bidadi Rajashekaraiah, Shafali Singh, Vijay Kanuru","doi":"10.4103/jomfp.jomfp_420_23","DOIUrl":null,"url":null,"abstract":"<p><strong>Context: </strong>Carbon monoxide (CO) concentrations in exhaled air may impart a quick, non-invasive method to determine smoking status. Haras is a nutraceutical medication, which is slowly gaining recognition for its antioxidant and anti-inflammatory activities.</p><p><strong>Aims: </strong>The effectiveness of the Haras therapy in smokers and non-smokers will be assessed by evaluating breath CO levels.</p><p><strong>Methods and materials: </strong>The study included 101 test subjects with 76 subjects of smokers and 25 subjects of non-smokers. Both the test groups were given 10 mL of Haras juice in divided doses per day for 30 days. The CO levels were evaluated using a breath analyser before drug trial and then on the 8<sup>th</sup>, 15<sup>th</sup>, 22<sup>nd</sup> and after the conclusion of the drug trial.</p><p><strong>Statistical analysis used: </strong>The Wilcoxon signed-rank test was used to compare the CO and carboxyhemoglobin levels among smokers and non-smokers.</p><p><strong>Results: </strong>Smokers had higher mean percent carboxyhemoglobin and mean parts per million CO values than non-smokers, and the difference between the two was shown to be statistically significant (<i>P</i> < 0.001). It was also found to be statistically significant from the first day to the eighth day, the first day to the 15<sup>th</sup> day, the first day to the 20<sup>th</sup> second day, first day to the 30<sup>th</sup> day (<i>P</i> < 0.001).</p><p><strong>Conclusions: </strong>Haras can be used effectively as an alternative supportive treatment for the diminution of CO levels in smokers and non-smokers.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 1","pages":"23-28"},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11126257/pdf/","citationCount":"0","resultStr":"{\"title\":\"Efficacy of nutritional supplement (Haras) on carbon monoxide levels in smokers and non-smokers: An observational study.\",\"authors\":\"Vidyadevi Chandavarkar, Mithilesh Narayan Mishra, Deepak Bhargava, Premalatha Bidadi Rajashekaraiah, Shafali Singh, Vijay Kanuru\",\"doi\":\"10.4103/jomfp.jomfp_420_23\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Context: </strong>Carbon monoxide (CO) concentrations in exhaled air may impart a quick, non-invasive method to determine smoking status. Haras is a nutraceutical medication, which is slowly gaining recognition for its antioxidant and anti-inflammatory activities.</p><p><strong>Aims: </strong>The effectiveness of the Haras therapy in smokers and non-smokers will be assessed by evaluating breath CO levels.</p><p><strong>Methods and materials: </strong>The study included 101 test subjects with 76 subjects of smokers and 25 subjects of non-smokers. Both the test groups were given 10 mL of Haras juice in divided doses per day for 30 days. The CO levels were evaluated using a breath analyser before drug trial and then on the 8<sup>th</sup>, 15<sup>th</sup>, 22<sup>nd</sup> and after the conclusion of the drug trial.</p><p><strong>Statistical analysis used: </strong>The Wilcoxon signed-rank test was used to compare the CO and carboxyhemoglobin levels among smokers and non-smokers.</p><p><strong>Results: </strong>Smokers had higher mean percent carboxyhemoglobin and mean parts per million CO values than non-smokers, and the difference between the two was shown to be statistically significant (<i>P</i> < 0.001). It was also found to be statistically significant from the first day to the eighth day, the first day to the 15<sup>th</sup> day, the first day to the 20<sup>th</sup> second day, first day to the 30<sup>th</sup> day (<i>P</i> < 0.001).</p><p><strong>Conclusions: </strong>Haras can be used effectively as an alternative supportive treatment for the diminution of CO levels in smokers and non-smokers.</p>\",\"PeriodicalId\":38846,\"journal\":{\"name\":\"Journal of Oral and Maxillofacial Pathology\",\"volume\":\"28 1\",\"pages\":\"23-28\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11126257/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Oral and Maxillofacial Pathology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/jomfp.jomfp_420_23\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/4/15 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Oral and Maxillofacial Pathology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/jomfp.jomfp_420_23","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/4/15 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Efficacy of nutritional supplement (Haras) on carbon monoxide levels in smokers and non-smokers: An observational study.
Context: Carbon monoxide (CO) concentrations in exhaled air may impart a quick, non-invasive method to determine smoking status. Haras is a nutraceutical medication, which is slowly gaining recognition for its antioxidant and anti-inflammatory activities.
Aims: The effectiveness of the Haras therapy in smokers and non-smokers will be assessed by evaluating breath CO levels.
Methods and materials: The study included 101 test subjects with 76 subjects of smokers and 25 subjects of non-smokers. Both the test groups were given 10 mL of Haras juice in divided doses per day for 30 days. The CO levels were evaluated using a breath analyser before drug trial and then on the 8th, 15th, 22nd and after the conclusion of the drug trial.
Statistical analysis used: The Wilcoxon signed-rank test was used to compare the CO and carboxyhemoglobin levels among smokers and non-smokers.
Results: Smokers had higher mean percent carboxyhemoglobin and mean parts per million CO values than non-smokers, and the difference between the two was shown to be statistically significant (P < 0.001). It was also found to be statistically significant from the first day to the eighth day, the first day to the 15th day, the first day to the 20th second day, first day to the 30th day (P < 0.001).
Conclusions: Haras can be used effectively as an alternative supportive treatment for the diminution of CO levels in smokers and non-smokers.
期刊介绍：
The journal of Oral and Maxillofacial Pathology [ISSN:print-(0973-029X, online-1998-393X)] is a tri-annual journal published on behalf of “The Indian Association of Oral and Maxillofacial Pathologists” (IAOMP). The publication of JOMFP was started in the year 1993. The journal publishes papers on a wide spectrum of topics associated with the scope of Oral and Maxillofacial Pathology, also, ensuring scientific merit and quality. It is a comprehensive reading material for the professionals who want to upgrade their diagnostic skills in Oral Diseases; allows exposure to newer topics and methods of research in the Oral-facial Tissues and Pathology. New features allow an open minded thinking and approach to various pathologies. It also encourages authors to showcase quality work done by them and to compile relevant cases which are diagnostically challenging. The Journal takes pride in maintaining the quality of articles and photomicrographs.
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