重症监护病房的儿科紧急腹膜透析:适应症、技术和结果。

IF 2.2 3区 医学 Q3 HEMATOLOGY Blood Purification Pub Date : 2024-01-01 Epub Date: 2024-05-26 DOI:10.1159/000539512
Yi-Hsuan Huang, Chia-Man Chou, Sheng-Yang Huang, Hou-Chuan Chen
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引用次数: 0

摘要

导言:本研究旨在确定影响因各种原因需要紧急腹膜透析(PD)的儿科患者预后的风险因素,重点关注生存率、肾功能恢复、腹膜透析持续时间、并发症和生活质量:对2010年1月至2023年2月期间在重症监护室接受紧急床旁腹膜透析的儿科患者的病历进行了回顾性分析。共放置了 34 根导管,并收集了人口统计学、术前和手术数据。使用 MedCalc® 统计软件进行分析,显著性水平设定为 p <0.05。术前使用了预防性抗生素,导管由一个小儿外科医生团队以统一的技术置入:置入导管时的中位年龄为 39 天(范围 2-2286),中位体重为 3.53 千克(范围 1.2-48.8)。大多数为男性(64.7%),17.6%为早产儿。最常见的腹膜透析适应症是 AKI(88.2%),其次是高氨血症、代谢性酸中毒和腹腔隔室综合征。置入透析器的中位等待时间为一天,中位持续时间为七天。并发症包括透析液渗漏(22.8%)和导管阻塞导致腹膜透析中止(31.4%)。死亡率高达 71.4%:结论:对于心脏手术后的小儿患者,提倡尽早开始透析是明智的。AKI是导致死亡的重要风险因素,而早产则会增加透析液渗漏的风险。网膜切除术和导管出口方法对预后没有显著影响。这项研究的局限性突出表明,需要进行更大规模的前瞻性研究,以更好地了解和改善这一弱势群体的紧急透析管理。
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Pediatric Emergent Peritoneal Dialysis in Intensive Care Units: Indications, Techniques, and Outcomes.

Introduction: This study aimed to identify risk factors affecting outcomes in pediatric patients requiring emergent peritoneal dialysis (PD) for all causes, focusing on survival rates, kidney function recovery, PD duration, complications, and quality of life.

Methods: A retrospective review was conducted on medical records of pediatric patients who received emergent bedside PD in the intensive care unit from January 2010 to February 2023. Thirty-four catheters were placed, with demographic, preoperative, and procedural data collected. MedCalc® Statistical Software was used for analysis with a significance level set at p < 0.05. Prophylactic antibiotics were administered prior to surgery, and catheters were placed using a consistent technique by a single team of pediatric surgeons.

Results: The median age at catheter placement was 39 days (range 2-2,286), and the median body weight was 3.53 kg (range 1.2-48.8). The majority were male (64.7%), with 17.6% preterm. The most common indication for PD was acute kidney injury (AKI) (88.2%), followed by hyperammonemia, metabolic acidosis, and abdominal compartment syndrome. The median waiting period for PD placement was 1 day, and the median duration of PD was 7 days. Complications included dialysate leakage (22.8%) and catheter obstruction leading to PD discontinuation (31.4%). The mortality rate was high at 71.4%.

Conclusion: It is advisable to advocate for the early initiation of PD in pediatric patients following cardiac surgery. AKI is a significant risk factor for mortality, while prematurity increases the risk of dialysate leakage. Omentectomy and the method of catheter exit did not significantly affect outcomes. The study's limitations highlight the need for larger prospective studies to better understand and improve emergent PD management in this vulnerable population.

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来源期刊
Blood Purification
Blood Purification 医学-泌尿学与肾脏学
CiteScore
5.80
自引率
3.30%
发文量
69
审稿时长
6-12 weeks
期刊介绍: Practical information on hemodialysis, hemofiltration, peritoneal dialysis and apheresis is featured in this journal. Recognizing the critical importance of equipment and procedures, particular emphasis has been placed on reports, drawn from a wide range of fields, describing technical advances and improvements in methodology. Papers reflect the search for cost-effective solutions which increase not only patient survival but also patient comfort and disease improvement through prevention or correction of undesirable effects. Advances in vascular access and blood anticoagulation, problems associated with exposure of blood to foreign surfaces and acute-care nephrology, including continuous therapies, also receive attention. Nephrologists, internists, intensivists and hospital staff involved in dialysis, apheresis and immunoadsorption for acute and chronic solid organ failure will find this journal useful and informative. ''Blood Purification'' also serves as a platform for multidisciplinary experiences involving nephrologists, cardiologists and critical care physicians in order to expand the level of interaction between different disciplines and specialities.
期刊最新文献
First In Human Rapid Removal of Circulating Tumor Cells in Solid Metastatic Neoplasia By Microbind Affinity Blood Filter. Ultrasonographic Evaluation of Systemic Venous Congestion in Maintenance Hemodialysis Patients During Fluid Removal. Use of cardiac troponin assays in hemodialysis patients. Removal of meropenem and piperacillin during experimental hemoadsorption with the HA380 cartridge. Reduction Rate of Uric Acid in Blood During Continuous Renal Replacement Therapy for Acute Kidney Injury: A Multicenter Retrospective Observational Study.
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