Tong Shen, Xiang-Tao Zha, Mei Yu, Guo-Li Li, Yi-Lin He
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A pair epimers of eremophilane sesquiterpene from Ligularia macrophylla
Two oxygenated eremophilane-type sesquiterpenoids, possessing C21 skeleton, a pair epimers, have been isolated from the whole plants of Ligularia macrophylla (Compositae). Their structures were determined by analysis of infrared, ultraviolet, nuclear magnetic resonance, high-resolution electrospray ionization mass spectrometry data, and electronic circular dichroism as well as comparison with literature data. Of the two compounds, the compound 1 is unknown, and the other is known. These compounds are evaluated for antibacterial activity of Staphylococcus aureus, Escherichia coli, Bacillus subtilis, and Bacillus cereus.
期刊介绍：
The Journal of Chemical Research is a monthly journal which has a broad international authorship and publishes research papers and reviews in all branches of experimental chemistry. Established in 1977 as a joint venture by the British, French and German chemical societies it maintains the high standards set by the founding societies. Each paper is independently peer reviewed and only carefully evaluated contributions are accepted. Recent papers have described new synthetic methods, new heterocyclic compounds, new natural products, and the inorganic chemistry of metal complexes.
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