一名患有颅内成熟畸胎瘤的儿科患者因副肿瘤综合征导致血管痉挛并继发中风：病例报告。

IF 1.3 4区医学 Q4 CLINICAL NEUROLOGY Child's Nervous System Pub Date : 2024-09-01 Epub Date: 2024-05-31 DOI:10.1007/s00381-024-06471-z

Amanda V Jenson, Ali Yunus Rizvi, Rebecca A Reynolds, Sara Hartnett-Wright, Thomas J Gellar, Stacie Stapleton, Ignacio Gonzalez-Gomez, S Hassan A Akbari, Matthew D Smyth

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引用次数: 0

摘要

畸胎瘤占所有颅内生殖细胞瘤的18%-20%，大多发生在松果体区，文献中仅描述了几例小儿蝶鞍和鞍上畸胎瘤。在此，我们介绍了一例颅内成熟畸胎瘤患儿的病例，该畸胎瘤具有胰腺特征，导致血管痉挛并继发脑卒中，其CDKN2A阳性--这是一种与恶性肿瘤和导致脑卒中的小血管疾病相关的独立变异。

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Vasospasm and subsequent stroke from paraneoplastic syndrome in a pediatric patient with an intracranial mature teratoma: a case report.

Teratomas account for 18-20% of all intracranial germ cell tumors and mostly occur in the pineal region with only a few cases of pediatric sellar and suprasellar teratomas described in the literature. Here, we present a case of a child with an intracranial mature teratoma with pancreatic features causing vasospasm and subsequent stroke, found to be positive for CDKN2A-an independent variant associated with malignancy and small vessel disease leading to stroke.

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来源期刊

Child's Nervous System 医学-临床神经学

CiteScore

3.00

自引率

7.10%

发文量

322

审稿时长

3 months

期刊介绍： The journal has been expanded to encompass all aspects of pediatric neurosciences concerning the developmental and acquired abnormalities of the nervous system and its coverings, functional disorders, epilepsy, spasticity, basic and clinical neuro-oncology, rehabilitation and trauma. Global pediatric neurosurgery is an additional field of interest that will be considered for publication in the journal.