2023 EULAR 手部骨关节炎分类标准。

IF 20.3 1区 医学 Q1 RHEUMATOLOGY Annals of the Rheumatic Diseases Pub Date : 2024-10-21 DOI:10.1136/ard-2023-225073
Ida K Haugen, David T Felson, Abhishek Abhishek, Francis Berenbaum, Sita Bierma-Zeinstra, Krysia S Dziedzic, John James Edwards, Martin Englund, Merete Hermann-Eriksen, Gabriel Herrero-Beaumont, Catherine Hill, Mariko L Ishimori, Helgi Jonsson, Teemu Karjalainen, Ying Ying Leung, Emmanuel Maheu, Christian D Mallen, Michelle Marshall, Rikke H Moe, Roberta Ramonda, Valentin Ritschl, Marco Jpf Ritt, Tanja A Stamm, Zoltan Szekanecz, Florus van der Giesen, Lotte A van de Stadt, Coen van der Meulen, Ruth Wittoek, Elsie Greibrokk, Hellen Laheij, Margreet Kloppenburg
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引用次数: 0

摘要

研究目的本研究的目的是根据自我报告的数据和放射学特征,制定整体手部骨关节炎(OA)、指间OA和拇指基底OA的分类标准:方法:分类标准集分三个阶段制定。在第一阶段,我们确定了区分手部 OA 和对照组的标准。在第 2 阶段,我们采用基于共识的决策分析方法,得出基于临床医生的标准相对重要性评估。在第三阶段,我们完善了评分系统,确定了疾病分类的临界值,并比较了欧洲风湿病学协会联盟(EULAR)标准与 1990 年美国风湿病学会(ACR)标准的敏感性和特异性:结果:对于有手部症状且无其他疾病(包括银屑病)或急性损伤可解释手部症状的患者(强制性标准),可根据年龄、晨僵持续时间、有骨质增生和关节间隙狭窄的关节数量以及症状与影像学检查结果的一致性对手部 OA 进行分类。根据每个诊断要素的得分总和,如果一个人在 0-15 分的量表上达到 9 分或以上,就可以对其整体手部 OA 进行分类。指骨间 OA 和拇指基底 OA 的临界值为 8 分。在第一阶段的数据集中,EULAR标准的灵敏度高于ACR标准,但在两个外部队列中,两套标准的表现相似:结论:国际专家制定了 EULAR 标准,在临床研究中采用严格的方法对整体手部 OA、指间 OA 和拇指基底 OA 进行分类。
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2023 EULAR classification criteria for hand osteoarthritis.

Objectives: The objective of this study is to develop classification criteria for overall hand osteoarthritis (OA), interphalangeal OA and thumb base OA based on self-reported data and radiographic features.

Methods: The classification criteria sets were developed in three phases. In phase 1, we identified criteria that discriminated hand OA from controls. In phase 2, we used a consensus-based decision analysis approach to derive a clinician-based evaluation of the relative importance of the criteria. In phase 3, we refined the scoring system, determined the cut-offs for disease classification and compared the sensitivity and specificity of the European Alliance of Associations for Rheumatology (EULAR) criteria with the 1990 American College of Rheumatology (ACR) criteria.

Results: In persons with hand symptoms and no other disease (including psoriasis) or acute injury that can explain the hand symptoms (mandatory criteria), hand OA can be classified based on age, duration of morning stiffness, number of joints with osteophytes and joint space narrowing, and concordance between symptoms and radiographic findings. Using a sum of scores based on each diagnostic element, overall hand OA can be classified if a person achieves 9 or more points on a 0-15 scale. The cut-off for interphalangeal OA and thumb base OA is 8 points. While the EULAR criteria demonstrated better sensitivity than the ACR criteria in the phase 1 data set, the performance of the two criteria sets was similar in two external cohorts.

Conclusions: International experts developed the EULAR criteria to classify overall hand OA, interphalangeal OA and thumb base OA in clinical studies using a rigorous methodology.

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来源期刊
Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases 医学-风湿病学
CiteScore
35.00
自引率
9.90%
发文量
3728
审稿时长
1.4 months
期刊介绍: Annals of the Rheumatic Diseases (ARD) is an international peer-reviewed journal covering all aspects of rheumatology, which includes the full spectrum of musculoskeletal conditions, arthritic disease, and connective tissue disorders. ARD publishes basic, clinical, and translational scientific research, including the most important recommendations for the management of various conditions.
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