Thoudam Chanchan Devi, Ngasepam Bhogenjit Singh, Thiyam David Singh
{"title":"柠檬酸盐对湿化学沉淀法合成的羟基磷灰石纳米粒子形态和结构特性的影响","authors":"Thoudam Chanchan Devi, Ngasepam Bhogenjit Singh, Thiyam David Singh","doi":"10.1134/S1061933X24600027","DOIUrl":null,"url":null,"abstract":"<p>Hydroxyapatite (HAp) nanoparticles organically modified with citrate group are fabricated via a simple wet chemical precipitation method. The as-synthesized nanoparticles are structurally characterized by TEM, XRD, FT-IR, EDAX and dynamic light scattering (DLS) to investigate in detail the influence of surface coating ligand i.e. citrate on HAp morphology, crystal structure, phase and colloidal stability of the particles. Production of single phase with hexagonal crystal structure is evident by XRD analysis. The work shows mesoporous structure could be synthesized under the influence of citrate as confirmed by TEM image and N<sub>2</sub> adsorption−desorption isotherm. The experimental results indicate that citrate strongly influences HAp crystallization giving reduced particle size and uniform distribution. BET and BJH analysis indicate large surface area 135.74 m<sup>2</sup>/g and pore diameter of 9.86 nm with a total pore volume of 0.41 cm<sup>3</sup>/g respectively for 1 : 1 citrate to calcium ion molar ratio. The appropriate surface area and pore entrance significantly indicate potentiality to apply into biomedical fields as drug loading/delivery application.</p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effect of Citrate on Morphological and Structural Properties of Hydroxyapatite Nanoparticles Synthesized by Wet Chemical Precipitation Method\",\"authors\":\"Thoudam Chanchan Devi, Ngasepam Bhogenjit Singh, Thiyam David Singh\",\"doi\":\"10.1134/S1061933X24600027\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Hydroxyapatite (HAp) nanoparticles organically modified with citrate group are fabricated via a simple wet chemical precipitation method. The as-synthesized nanoparticles are structurally characterized by TEM, XRD, FT-IR, EDAX and dynamic light scattering (DLS) to investigate in detail the influence of surface coating ligand i.e. citrate on HAp morphology, crystal structure, phase and colloidal stability of the particles. Production of single phase with hexagonal crystal structure is evident by XRD analysis. The work shows mesoporous structure could be synthesized under the influence of citrate as confirmed by TEM image and N<sub>2</sub> adsorption−desorption isotherm. The experimental results indicate that citrate strongly influences HAp crystallization giving reduced particle size and uniform distribution. BET and BJH analysis indicate large surface area 135.74 m<sup>2</sup>/g and pore diameter of 9.86 nm with a total pore volume of 0.41 cm<sup>3</sup>/g respectively for 1 : 1 citrate to calcium ion molar ratio. The appropriate surface area and pore entrance significantly indicate potentiality to apply into biomedical fields as drug loading/delivery application.</p>\",\"PeriodicalId\":1,\"journal\":{\"name\":\"Accounts of Chemical Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":16.4000,\"publicationDate\":\"2024-05-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Accounts of Chemical Research\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1134/S1061933X24600027\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1134/S1061933X24600027","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Effect of Citrate on Morphological and Structural Properties of Hydroxyapatite Nanoparticles Synthesized by Wet Chemical Precipitation Method
Hydroxyapatite (HAp) nanoparticles organically modified with citrate group are fabricated via a simple wet chemical precipitation method. The as-synthesized nanoparticles are structurally characterized by TEM, XRD, FT-IR, EDAX and dynamic light scattering (DLS) to investigate in detail the influence of surface coating ligand i.e. citrate on HAp morphology, crystal structure, phase and colloidal stability of the particles. Production of single phase with hexagonal crystal structure is evident by XRD analysis. The work shows mesoporous structure could be synthesized under the influence of citrate as confirmed by TEM image and N2 adsorption−desorption isotherm. The experimental results indicate that citrate strongly influences HAp crystallization giving reduced particle size and uniform distribution. BET and BJH analysis indicate large surface area 135.74 m2/g and pore diameter of 9.86 nm with a total pore volume of 0.41 cm3/g respectively for 1 : 1 citrate to calcium ion molar ratio. The appropriate surface area and pore entrance significantly indicate potentiality to apply into biomedical fields as drug loading/delivery application.
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
