[内源性激素在近视发展中的作用和机制研究进展]。

X T Xu, X T Zhou
{"title":"[内源性激素在近视发展中的作用和机制研究进展]。","authors":"X T Xu, X T Zhou","doi":"10.3760/cma.j.cn112142-20231106-00213","DOIUrl":null,"url":null,"abstract":"<p><p>With the increasing prevalence of myopia among adolescents, the pathogenesis of this condition has garnered significant attention. Studies have discovered the expression of various hormone receptors in ocular tissues of both animals and humans. Additionally, changes in hormone levels accompany the development of myopia, although the exact relationships remain inconclusive. This article reviews the potential influences and mechanisms of action of endogenous hormones such as melatonin, serotonin, insulin, glucagon, sex hormones, vitamin D, and prostaglandins in ocular tissues including the retina, choroid, and sclera. It elaborates on the relationship between fluctuations in these hormone levels and the progression of myopia, aiming to provide guidance for exploring targets for myopia prevention and control.</p>","PeriodicalId":39688,"journal":{"name":"中华眼科杂志","volume":"60 6","pages":"547-558"},"PeriodicalIF":0.0000,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Advances in the study of the role and mechanisms of endogenous hormones in the development of myopia].\",\"authors\":\"X T Xu, X T Zhou\",\"doi\":\"10.3760/cma.j.cn112142-20231106-00213\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>With the increasing prevalence of myopia among adolescents, the pathogenesis of this condition has garnered significant attention. Studies have discovered the expression of various hormone receptors in ocular tissues of both animals and humans. Additionally, changes in hormone levels accompany the development of myopia, although the exact relationships remain inconclusive. This article reviews the potential influences and mechanisms of action of endogenous hormones such as melatonin, serotonin, insulin, glucagon, sex hormones, vitamin D, and prostaglandins in ocular tissues including the retina, choroid, and sclera. It elaborates on the relationship between fluctuations in these hormone levels and the progression of myopia, aiming to provide guidance for exploring targets for myopia prevention and control.</p>\",\"PeriodicalId\":39688,\"journal\":{\"name\":\"中华眼科杂志\",\"volume\":\"60 6\",\"pages\":\"547-558\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-06-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中华眼科杂志\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3760/cma.j.cn112142-20231106-00213\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华眼科杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/cma.j.cn112142-20231106-00213","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

摘要

随着青少年近视发病率的不断上升,近视的发病机理也引起了人们的极大关注。研究发现,各种激素受体在动物和人类的眼部组织中都有表达。此外,激素水平的变化伴随着近视的发展,但具体的关系仍无定论。本文回顾了褪黑激素、血清素、胰岛素、胰高血糖素、性激素、维生素 D 和前列腺素等内源性激素对视网膜、脉络膜和巩膜等眼组织的潜在影响和作用机制。报告阐述了这些激素水平的波动与近视发展之间的关系,旨在为探索近视防控目标提供指导。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
[Advances in the study of the role and mechanisms of endogenous hormones in the development of myopia].

With the increasing prevalence of myopia among adolescents, the pathogenesis of this condition has garnered significant attention. Studies have discovered the expression of various hormone receptors in ocular tissues of both animals and humans. Additionally, changes in hormone levels accompany the development of myopia, although the exact relationships remain inconclusive. This article reviews the potential influences and mechanisms of action of endogenous hormones such as melatonin, serotonin, insulin, glucagon, sex hormones, vitamin D, and prostaglandins in ocular tissues including the retina, choroid, and sclera. It elaborates on the relationship between fluctuations in these hormone levels and the progression of myopia, aiming to provide guidance for exploring targets for myopia prevention and control.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
中华眼科杂志
中华眼科杂志 Medicine-Ophthalmology
CiteScore
0.80
自引率
0.00%
发文量
12700
期刊最新文献
[Efficacy of modified nasal transposition of the split lateral rectus muscle for large-angle exotropia from oculomotor nerve palsy]. [Further raising prevention and treatment for amblyopia in China]. [Methotrexate therapy for primary intraocular lymphoma: a case report]. [Paying attention to problems and countermeasures in intermittent exotropia surgery]. [Paying attention to the management of blinding complications caused by early-onset high myopia in children].
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1