[云南省糖尿病视网膜病变的流行病学调查及风险因素]。

L Shi, X M Xia, X H Hou, J F Liu, X Nian, Y Jiang, Y X Song, Y S Xu
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引用次数: 0

摘要

为调查云南省糖尿病视网膜病变(DR)的患病率及流行病学特征,探讨其危险因素,为糖尿病(DM)慢性并发症的防治提供依据。本研究是一项大型横断面研究,共纳入2019年8月至11月期间云南省16个社区和村卫生服务中心登记在册的1524名DM患者。所有患者均完成了统一的问卷调查、人体测量、生化测量和辅助检查。采用 Logistic 回归分析筛选 DR 的风险因素。DR、轻度非增生性DR(mild-NPDR)和可转诊DR(RDR)的患病率分别为16.0%(244/1 524)、4.5%(69/1 524)和11.5%(175/1 524)。糖化血红蛋白 A1c(HbA1c)≥7.0% 是轻度-NPDR(OR=1.872,95%CI 1.055-3.323)和 RDR(OR=4.821,95%CI 2.917-7.969)的风险因素。血压≥130/80 mmHg(1 mmHg=0.133 kPa)是轻度 NPDR(OR=1.933,95%CI 1.112-3.358)和 RDR(OR=1.505,95%CI 1.063-2.130)的危险因素。在云南省,16.0%的DM患者伴有DR,其中约71.7%需要眼科转诊,DM患者RDR的高发生率与血糖和血压控制不佳有关。
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[Epidemiological investigation and risk factors of diabetic retinopathy in Yunnan Province].

To investigate the prevalence and epidemiological characteristics of diabetic retinopathy (DR) in Yunnan Province, explore its risk factors, and provide a basis for the prevention and treatment of chronic complications of diabetes mellitus (DM). This is a large cross-sectional study, in all, 1 524 DM patients in 16 communities and villages of Yunnan Province who were registered in health service centers were included in this study from August to November 2019. All patients completed a uniform questionnaire, anthropometric measurements, biochemical measurements, and auxiliary examinations. Logistic regression analysis was used to screen the risk factors of DR. The prevalence rates of DR, mild non-proliferative DR (mild-NPDR), and referable DR (RDR) were 16.0% (244/1 524), 4.5% (69/1 524), and 11.5% (175/1 524), respectively. Glycated hemoglobin A1c (HbA1c)≥7.0% was the risk factor of mild-NPDR (OR=1.872, 95%CI 1.055-3.323) and RDR (OR=4.821, 95%CI 2.917-7.969). Blood pressure≥130/80 mmHg (1 mmHg=0.133 kPa) was the risk factor of mild-NPDR (OR=1.933, 95%CI 1.112-3.358) and RDR (OR=1.505, 95%CI 1.063-2.130). In Yunnan Province, 16.0% DM patients had accompanying DR, wherein about 71.7% of them required an ophthalmology referral, and the high incidence of RDR in DM patients was associated with poor control of blood glucose and blood pressure.

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