用于全膝关节置换术的聚醚醚酮生物聚合物的体外磨损研究

Sandeep Kumar, K.V.S. Rajeswara Rao, Sunil R. Yalamalle
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引用次数: 0

摘要

如今,用于全膝关节置换的膝关节假体的平均寿命约为 10 至 15 年。如何防止这些假体出现故障一直是矫形外科医生和工程师的难题。假体失效的原因包括磨损、感染、不稳定和僵硬。造成失败的主要原因是假体的磨损和撕裂。在全膝关节置换术中,最常用的生物材料是钛合金 Ti6AI4V 和钴铬钼合金。其主要缺点是植入物仍会受到股骨部件与聚乙烯关节表面长期摩擦产生的微小超高分子量聚乙烯碎片的限制。因此,人们试图用高耐磨的生物材料来替代,以降低磨损率。本研究通过检测聚醚醚酮与 Ti6AI4V 的磨损性能,研究聚醚醚酮是否是适合用于全膝关节置换的材料。实验以不同的负载和速度进行。利用方差分析建立回归方程,对结果进行优化。
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In vitro wear investigation of polyether ether ketone biopolymer for total knee replacement
Nowadays, the average life span of knee prosthesis used in total knee replacement is approximately 10 to 15 years. The prevention of failure for these implants has been a constant struggle for orthopaedic surgeons and engineers. The reason behind for implant failures includes wear, infection, instability and stiffness. The major causes of failure are wear and tear of prosthesis. The most common biomaterials used in total knee replacement rubbing against a mating component of ultra-high-molecular-weight polyethylene are titanium alloy Ti6AI4V and alloy CoCrMo. The main drawback is that implants are still restrained by tiny ultra-high molecular weight poly debris generated by long term friction between femoral component and polyethylene articulating surface. Hence, the attempt is made to reduce the wear rate by replacing with high wear-resisting biomaterial. This research investigated whether polyether ether ketone was the appropriate material for total knee replacement by examining wear performance against Ti6AI4V. The experiments are conducted with different loading and speeds. The results are optimized by developing the regression equation using analysis of variance.
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来源期刊
Russian Journal of Biomechanics
Russian Journal of Biomechanics Biochemistry, Genetics and Molecular Biology-Biophysics
CiteScore
1.10
自引率
0.00%
发文量
0
期刊介绍: Russian Journal of Biomechanics publishes peer reviewed articles related to the principal topics in biomechanics. This Journal was established to improve the information interchange between specialists on biomechanics from Russia and other countries. Biomechanics is defined as the mechanics of living tissues and biomaterials. The Journal presents original papers of a wide biomechanical profile. A balance of biomechanical and medical problems is the principal aspect of the Journal activities. The Journal encourages the submission of original articles, reviews, short communications and case studies in all areas of biomechanics, including, but not limited to: • General problems and methods of biomechanics • Rheological properties of living tissues • Biomaterials and prostheses • Dental biomechanics • Human movement analysis • Musculoskeletal biomechanics • Cardiovascular biomechanics • Biomechanics of breathing • Tissue and cellular biomechanics • Sport biomechanics • Biomechanical problems in biotechnology.
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