Effect of cryolipolysis on hormonal profile and menstrual regulation in obese women with polycystic ovarian syndrome

Background: Polycystic ovarian syndrome (PCOS) is a frequent disease in women that affects their ability to reproduce, their metabolism, and their ability to control their androgen levels. It is brought on by an imbalance of female sex hormones as well as being aggravated by obesity. Purpose: To examine the effects of cryolipolysis on hormonal profile and menstrual regularity in obese women with PCOS. Methods: 50 female patients, aged from 18 to 30 years, were split into two groups of 25 patients each at random. Group A (control group), treated by a diet regime and aerobic exercise for 12 weeks; Group B (study group): treated by the same diet regime and aerobic exercise as Group A in addition to cryolipolysis for 45 minutes per session, every 2 weeks for 12 weeks. Assessment of all females was carried out through measuring weight, body mass index (BMI), waist hip ratio, luteinizing hormone (LH), follicle-stimulating hormone (FSH), and insulin resistance (IR), in addition to menstrual regularity pre-and post-treatment. Results: There was a significant improvement (P<0.05) in all measured variable after treatment compared to before treatment in both group A and B, by comparing post treatment values there is a significant difference (p<0.05) in all measured variable favouring the study group (group B). Conclusions: Cryolipolysis in addition to diet regime and aerobic exercise has significant effect on hormonal profile as well as menstrual regularity in obese women suffering from PCOS.