基于残余屈光度预测假性白内障人群的视力

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-10-01 Epub Date: 2024-06-03 DOI:10.1080/02713683.2024.2359981
Johannes Weisensee, Otmar M Ringhofer, Achim Langenbucher
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引用次数: 0

摘要

目的:本研究旨在设计一种简单、方便的预测方法,用于预测球面和柱面屈光不正对不同距离视力下降的影响,并在临床数据集上对该模型进行验证:本研究对 35 名白内障手术后使用无像差眼内镜的患者的 70 只眼睛进行了检查。分析了生物计量学和角膜数据,并由两名经验丰富的验光师评估了主观屈光度和视力。研究计算了球面等值(SEQ),并通过向量加法计算了离焦等值(DEQ vec)和绝对值之和(DEQ abs)。采用单变量回归法建立了预测模型,并通过非参数引导法(10,000 个周期)计算出置信区间(BCa 95%):计算出的各种等值包括:球面等值(SEQ)为-0.44 D,基于向量计算的离焦等值(DEQ vec)为 0.70 D,基于绝对值的离焦等值(DEQ abs)为 0.89 D。未矫正视力和矫正视力的平均值分别为 0.07 logMAR 和 -0.04 logMAR。绝对离焦等效值(DEQ abs)的置信区间(BCa 95%)最小,为 0.07:基于绝对值相加的散焦等效值(DEQ abs)是上述应用中最实用的预测指标。值得注意的是,它通过一个简单的等式提供了易于计算的优势:VA 损失 = DEQ abs ⋅ 0.23。在 95% 的情况下,这种预测损耗的精确度为 ±0.03 线。
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Prediction of Visual Acuity in Pseudophakic Cataract Population Based on Residual Refraction.

Purpose: The purpose of the study was to design a simple, handy prediction for the effect of spherical and cylindrical refractive error on the visual acuity degradation at different distances and validate this model on a clinical dataset.

Methods: This study examined 70 eyes from 35 patients' post-cataract surgery with aberration-free intraocular lenses. Biometric and corneal data were analysed, and subjective refraction and visual acuity were evaluated by two experienced optometrists. The study computed the spherical equivalent (SEQ), and defocus equivalent via vector addition (DEQ vec), as the sum of absolute values (DEQ abs). Predictive models were developed using univariate regression, with confidence intervals (BCa 95%) calculated through non-parametric bootstrapping (10,000 cycles).

Results: Various calculated equivalents included -0.44 D for spherical equivalent (SEQ), 0.70 D for defocus equivalent based on vector calculation (DEQ vec), and 0.89 D for defocus equivalent based on absolute values (DEQ abs). Uncorrected and corrected visual acuity averaged 0.07 logMAR and -0.04 logMAR, respectively. The absolute defocus equivalent (DEQ abs) exhibited the smallest confidence interval (BCa 95%) at 0.07.

Conclusion: The defocus equivalent based on the addition of absolute values (DEQ abs) emerged as the most practical predictor for the described applications. Notably, it offers the advantage of easy calculability through a simple equation: VA loss = DEQ abs ⋅ 0.23. In 95% of cases, this predicted loss would have an accuracy of ±0.03 lines.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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