[风湿病中的慢性乙型肝炎:筛查和感染再激活问题:综述]。

Pub Date : 2024-06-03 DOI:10.26442/00403660.2024.05.202707
G I Gridneva, B S Belov, E S Aronova
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引用次数: 0

摘要

感染了乙型肝炎病毒(HBV)的风湿病患者是很难治疗的,这不仅是因为他们存在发生肝硬化和肝硬化快速进展的危险因素,还因为这种感染很可能再次活化。尽管在抗击 HBV 的斗争中取得了一定的成绩,但由于该病存在隐匿形式,风湿病学家和感染学家的视线无法捕捉到,因此无法完全战胜该病毒。根据对现有出版物的分析结果,本文提出了在处方抗风湿治疗时对风湿病患者进行全面免疫学筛查的理由。文中讨论了 COVID-19 在慢性乙型病毒性肝炎病情加重中的作用、抗病毒预防和监测等问题,并根据 HBV 再激活的风险对抗风湿药物进行了分类。
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[Chronic hepatitis B in rheumatic diseases: issues of screening and reactivation of infection: A review].

Patients with rheumatic diseases infected with hepatitis B virus (HBV) are difficult to manage not only due to the presence of risk factors for the development and rapid progression of liver cirrhosis, but also due to the likelihood of reactivation of this infection. Despite the successes achieved in the fight against HBV, the virus cannot be completely defeated due to the presence of hidden forms of the disease, escaping the field of vision of a rheumatologist and an infectionist. Based on the results of the analysis of current publications, the paper presents the rationale for a complete immunological screening of patients with rheumatic diseases when prescribing antirheumatic therapy. The issues of the role of COVID-19 in the exacerbation of chronic viral hepatitis B, antiviral prevention and monitoring are discussed, the classification of antirheumatic drugs according to the risk of HBV reactivation is presented.

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