用含有扁桃酸的乙酰化淀粉/κ-卡拉胶混合物制备天然伤口敷料膜

IF 0.7 Q4 MATERIALS SCIENCE, MULTIDISCIPLINARY Journal of metals, materials and minerals Pub Date : 2024-06-04 DOI:10.55713/jmmm.v34i2.1984

Wimolsiri Sriphochai, J. Prachayawarakorn

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引用次数: 0

摘要

由于乙酰化淀粉膜在伤口敷料应用中存在机械性能低、无抗菌活性等局限性，因此采用不同含量的κ-卡拉胶和扁桃酸对乙酰化淀粉膜进行改性。红外光谱证实了改性乙酰化淀粉膜中含有κ-卡拉胶和扁桃酸。此外，通过扫描电子显微镜观察，卡拉胶改性乙酰化淀粉薄膜的结晶度降低，薄膜更加光滑。此外，在改性乙酰化淀粉薄膜中添加不同量的κ-卡拉胶可改善薄膜的机械性能、吸湿性、水蒸气透过率（WVTR）和膨胀度。此外，添加了 20 wt% 的扁桃酸的κ-卡拉胶改性乙酰化淀粉膜对金黄色葡萄球菌和大肠杆菌都具有抗菌性能。此外，还研究了添加不同量扁桃酸的κ-卡拉胶改性乙酰化淀粉膜的结晶度、机械性能、吸湿性、WVTR、膨胀度、抗菌活性和细胞毒性。

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Natural wound dressing films prepared from acetylated starch/κ-carrageenan blend incorporated with mandelic acid

Due to several limitations of acetylated starch film for wound dressing applications such as low mechanical properties and no antibacterial activity, acetylated starch film was, therefore, modified by different contents of κ-carrageenan and mandelic acid. Infrared spectra confirmed the presence of κ-carrageenan and mandelic acid in the modified acetylated starch films. In addition, the decreased crystallinity of the carrageenan modified acetylated starch films led to more smooth film, as observed by scanning electron images. Besides, the addition of various amounts of κ-carrageenan in the modified acetylated starch films caused the improvement of mechanical properties, moisture uptake, water vapor transmission rate (WVTR), and degree of swelling. Moreover, κ-carrageenan modified acetylated starch film loaded with 20 wt% of mandelic acid exhibited antibacterial property against both S.aureus and E.coli bacteria. Additionally, degree of crystallinity, mechanical properties, moisture uptake, WVTR, degree of swelling, antibacterial activity, and cytotoxicity of κ-carrageenan modified acetylated starch films added by different amounts of mandelic acid were also studied.

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来源期刊

Journal of metals, materials and minerals MATERIALS SCIENCE, MULTIDISCIPLINARY-

CiteScore

1.40

自引率

11.10%

发文量

期刊介绍： Journal of Metals, Materials and Minerals (JMMM) is a double-blind peer-reviewed international journal published 4 issues per year (starting from 2019), in March, June, September, and December, aims at disseminating advanced knowledge in the fields to academia, professionals and industrialists. JMMM publishes original research articles as well as review articles related to research and development in science, technology and engineering of metals, materials and minerals, including composite & hybrid materials, concrete and cement-based systems, ceramics, glass, refractory, semiconductors, polymeric & polymer-based materials, conventional & technical textiles, nanomaterials, thin films, biomaterials, and functional materials.