{"title":"通过巴比妥酸/硫代巴比妥酸、酰基苯肼和芳基乙二醛之间的三组分反应高效合成吡唑基巴比妥酸盐","authors":"Nasim Tajaddini , Mohammad Anary-Abbasinejad","doi":"10.1080/00397911.2024.2356640","DOIUrl":null,"url":null,"abstract":"<div><p>An effective protocol for synthesis of some new pyrazolylbarbiturate derivatives is reported through a one-pot, three-component reaction between barbituric/thiobarbituric acid, aroylphenylhydrazones and arylglyoxal derivatives. All reactions were conducted in ethanol as solvent without using any catalyst and products were obtained by simple filtering of the precipitated solids in high yields. All products were characterized by <sup>1</sup>H and <sup>13</sup>C NMR and IR spectral and elemental analysis data.</p></div>","PeriodicalId":22119,"journal":{"name":"Synthetic Communications","volume":null,"pages":null},"PeriodicalIF":1.8000,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"An efficient synthesis of pyrazolylbarbiturates by three-component reaction between barbituric/thiobarbituric acid, aroylphenylhydrazones and arylglyoxals\",\"authors\":\"Nasim Tajaddini , Mohammad Anary-Abbasinejad\",\"doi\":\"10.1080/00397911.2024.2356640\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>An effective protocol for synthesis of some new pyrazolylbarbiturate derivatives is reported through a one-pot, three-component reaction between barbituric/thiobarbituric acid, aroylphenylhydrazones and arylglyoxal derivatives. All reactions were conducted in ethanol as solvent without using any catalyst and products were obtained by simple filtering of the precipitated solids in high yields. All products were characterized by <sup>1</sup>H and <sup>13</sup>C NMR and IR spectral and elemental analysis data.</p></div>\",\"PeriodicalId\":22119,\"journal\":{\"name\":\"Synthetic Communications\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2024-05-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Synthetic Communications\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/org/science/article/pii/S0039791124000493\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Synthetic Communications","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S0039791124000493","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
摘要
通过巴比妥酸/硫代巴比妥酸、酰基苯肼和芳基乙二醛衍生物之间的单锅三组分反应，报告了合成一些新的吡唑巴比妥酸衍生物的有效方案。所有反应均在乙醇溶剂中进行，无需使用任何催化剂，通过简单过滤沉淀的固体即可获得高产率的产物。所有产物均通过 1H、13C NMR 和 IR 光谱及元素分析数据进行表征。
An efficient synthesis of pyrazolylbarbiturates by three-component reaction between barbituric/thiobarbituric acid, aroylphenylhydrazones and arylglyoxals
An effective protocol for synthesis of some new pyrazolylbarbiturate derivatives is reported through a one-pot, three-component reaction between barbituric/thiobarbituric acid, aroylphenylhydrazones and arylglyoxal derivatives. All reactions were conducted in ethanol as solvent without using any catalyst and products were obtained by simple filtering of the precipitated solids in high yields. All products were characterized by 1H and 13C NMR and IR spectral and elemental analysis data.
期刊介绍：
Synthetic Communications presents communications describing new methods, reagents, and other synthetic work pertaining to organic chemistry with sufficient experimental detail to permit reported reactions to be repeated by a chemist reasonably skilled in the art. In addition, the Journal features short, focused review articles discussing topics within its remit of synthetic organic chemistry.
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