利用组胺乳清试验检测外用公平制剂中的类固醇

IF 1.9 Q3 DERMATOLOGY Indian Dermatology Online Journal Pub Date : 2024-02-13 eCollection Date: 2024-05-01 DOI:10.4103/idoj.idoj_321_23

Satish Nithya, Chakravarthi R Srinivas, Surendranath Lal

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引用次数: 0

摘要

外用皮质类固醇（TC）滥用是一个普遍的世界性问题。最近新出现的问题之一是在美白霜中掺入 TC。美白面霜中是否含有 TC 可通过高效液相色谱法（HPLC）进行检测。由于高效液相色谱法价格昂贵、耗时且不易获得，我们建议使用组胺喘息试验作为一种简单而廉价的检测方法，来检测美白霜中是否含有外用类固醇。

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Detection of Steroids in Topical Fairness Preparations Using Histamine Wheal Test.

Topical corticosteroid (TC) abuse is a common, worldwide, problem. One of the recent emerging concerns is the adulteration of TC in fairness cream. The presence of TC in skin-whitening cosmetic creams can be detected by high-performance liquid chromatography (HPLC). Since HPLC is expensive, time-taking and not easily available, we suggest the use of histamine wheal test as a simple and inexpensive test to detect the presence of topical steroids in fairness cream.

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