显微镜下血尿并不能预测儿童腹腔内损伤的临床意义。

IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pediatric emergency care Pub Date : 2024-08-01 Epub Date: 2024-06-07 DOI:10.1097/PEC.0000000000003210
Stephanie C Papillon, Christopher P Pennell, Shannara E Bauer, Aubrey DiBello, Sahal A Master, Rajeev Prasad, L Grier Arthur, Harsh Grewal
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引用次数: 0

摘要

目的:儿童腹腔内钝性损伤筛查通常包括指导计算机断层扫描的实验室评估。我们试图评估尿液分析在识别具有临床意义的腹腔内损伤(ci-IAI)患者中的应用:我们对 2016 年至 2019 年期间在一级创伤中心就诊的所有 18 岁以下钝性机制患者进行了回顾性病历审查。排除标准包括从外部机构转来、身体虐待以及在到达后三十分钟内死亡。对患者的人口统计学特征、体格检查结果、血清化学成分、尿液分析和影像学检查进行了审查。有临床意义的腹腔内损伤是指需要≥2晚入院、输血、血管造影栓塞或治疗性手术的损伤:结果:共发现 240 名患者。165 名患者完成了尿检。在所有患者中,化验单异常和体格检查异常的灵敏度为 88.9%,阴性预测值为 99.3%。九名患者有 ci-IAI.有 ci-IAI 的患者更有可能出现腹痛、检查时触痛和肝酶升高。如果根据患者是否存在显微镜下血尿、化学或体格检查是否异常进行分层,尿液分析并不能提高鉴别 ci-IAI 患者的能力。事实上,出现镜下血尿会使假阳性率增加 12%:显微镜下血尿不是颅内损伤的有效标志,可能导致误判为更严重的损伤。
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Presence of Microscopic Hematuria Does Not Predict Clinically Important Intra-Abdominal Injury in Children.

Objective: Screening for blunt intra-abdominal injury in children often includes directed laboratory evaluation that guides need for computed tomography. We sought to evaluate the use of urinalysis in identifying patients with clinically important intraabdominal injury ( ci -IAI).

Methods: A retrospective chart review was performed for all patients less than 18 years who presented with blunt mechanisms at a level I trauma center between 2016 and 2019. Exclusion criteria included transfer from an outside facility, physical abuse, and death within thirty minutes of arrival. Demographics, physical exam findings, serum chemistries, urinalysis, and imaging were reviewed. Clinically important intraabdominal injury was defined as injury requiring ≥2 nights admission, blood transfusion, angiography with embolization, or therapeutic surgery.

Results: Two hundred forty patients were identified. One hundred sixty-five had a completed urinalysis. For all patients an abnormal chemistry panel and abnormal physical exam had a sensitivity of 88.9% and a negative predictive value of 99.3%. Nine patients had a ci -IAI. Patients with a ci -IAI were more likely to have abdominal pain, tenderness on exam, and elevated hepatic enzymes. When patients were stratified by the presence of an abnormal chemistry or physical exam with or without microscopic hematuria, urinalysis did not improve the ability to identify patients with a ci -IAI. In fact, presence of microscopic hematuria increased the rate of false positives by 12%.

Conclusions: Microscopic hematuria was not a useful marker for ci -IAI and may lead to falsely assuming a more serious injury.

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来源期刊
Pediatric emergency care
Pediatric emergency care 医学-急救医学
CiteScore
2.40
自引率
14.30%
发文量
577
审稿时长
3-6 weeks
期刊介绍: Pediatric Emergency Care®, features clinically relevant original articles with an EM perspective on the care of acutely ill or injured children and adolescents. The journal is aimed at both the pediatrician who wants to know more about treating and being compensated for minor emergency cases and the emergency physicians who must treat children or adolescents in more than one case in there.
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