全髋关节置换术后,80 岁或以上患者的功能结果和满意度与年轻患者(65 至 75 岁)无临床差异。

IF 3.4 2区 医学 Q1 ORTHOPEDICS Journal of Arthroplasty Pub Date : 2024-12-01 Epub Date: 2024-06-06 DOI:10.1016/j.arth.2024.05.088
Jad Wehbe, Samantha Jones, Gregory Hodgson, Irrum Afzal, Nicholas D Clement, David H Sochart
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引用次数: 0

摘要

导言:随着人口老龄化的加剧,需要进行全髋关节置换术(THA)的老年患者比例也在增加,但目前尚不清楚年龄是否会独立影响手术效果。研究旨在评估≥80岁患者与65至75岁患者进行全髋关节置换术后的功能、生活质量(QoL)和满意度,并对混杂因素进行调整:方法:2010年至2019年期间进行了一项单中心回顾性队列研究。共有 2367 例 THAs 为年龄≥ 80 岁的患者实施,5113 例为 65 至 75 岁的患者实施。记录了人口统计学数据和住院时间(LOS)。收集了术前和术后两年的牛津髋关节评分(OHS)、EuroQol(EQ-5D)和满意度评分。有临床意义的差异定义为牛津髋关节评分(OHS)达到 5 分,EQ-5D 实用性达到 0.085。进行回归分析以调整混杂因素:结果:≥80 岁组患者更多是女性(P < 0.001),美国麻醉学会(ASA)等级更高(P < 0.001),术前 OHS 更差(平均差(MD)2.3,P < 0.001),EQ-5D 更差(MD 0.087,P < 0.001)。两个年龄组的患者在术后2年的OHS和EQ-5D效用方面都取得了有临床意义和统计学意义(P < 0.001)的改善。在对混杂变量进行调整后,≥ 80 岁年龄组的 OHS(MD -1.9分)和 EQ-5D(MD -0.055 实用性)改善幅度明显较低(P < 0.001),但没有临床意义。组间满意度无差异(P = 0.813)。在对混杂变量进行调整后,年龄≥80 岁组的患者延长生命周期的风险增加(几率比 1.27,P < 0.001):不同年龄组在髋关节特异性结果或与健康相关的生活质量方面没有临床意义上的差异,两组患者对结果的满意度相同。不过,年龄较大者的住院时间确实较长。
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Functional Outcomes and Satisfaction Rates in Patients Aged 80 Years or Older are Not Clinically Different From Their Younger (65 to 75 Years) Counterparts Following Total Hip Arthroplasty.

Background: As the population ages, the proportion of elderly patients requiring total hip arthroplasty (THA) increases, but it is not clear whether older age independently influences outcome. The aim was to assess function, quality of life, and satisfaction after THA in patients ≥ 80 years compared with those aged between 65 and 75 years when adjusting for confounding factors.

Methods: A single-center retrospective cohort study was performed between 2010 and 2019. A total 2,367 THAs were performed on patients ≥ 80 years and 5,113 on patients aged 65 to 75 years. The demographic data and length of stay (LOS) were recorded. Preoperative and 2-year postoperative Oxford Hip Scores (OHS), EuroQol (EQ-5D), and satisfaction scores were collected. Clinically meaningful difference was defined as 5 points in OHS and utility of 0.085 in EQ-5D. Regression analyses were performed to adjust for confounding factors.

Results: Patients in ≥ 80-years group were more likely women (P < .001), have higher American Society of Anesthesiolgists grade (P < .001), worse preoperative OHS (mean difference [MD] 2.3, P < .001), and EQ-5D (MD 0.087, P < .001). Both age groups achieved clinically meaningful and statistically significant (P < .001) improvement in OHS and EQ-5D utility at 2 years. When adjusting for confounding variables, the ≥ 80-year-old group had significantly (P < .001) lower improvement in OHS (MD -1.9 points) and EQ-5D (MD -0.055 utility), but these differences were not clinically meaningful. There was no difference (P = .813) in satisfaction between the groups. When adjusting for confounding variables, ≥ 80-year-old group had increased risk of longer LOS (odds ratio 1.27, P < .001).

Conclusions: There were no clinically meaningful differences in hip-specific outcome or health-related quality of life according to age group, and both were equally satisfied with their outcome. The older age group did, however, have longer LOS.

Level of evidence: Level III retrospective cohort study.

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来源期刊
Journal of Arthroplasty
Journal of Arthroplasty 医学-整形外科
CiteScore
7.00
自引率
20.00%
发文量
734
审稿时长
48 days
期刊介绍: The Journal of Arthroplasty brings together the clinical and scientific foundations for joint replacement. This peer-reviewed journal publishes original research and manuscripts of the highest quality from all areas relating to joint replacement or the treatment of its complications, including those dealing with clinical series and experience, prosthetic design, biomechanics, biomaterials, metallurgy, biologic response to arthroplasty materials in vivo and in vitro.
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