不孕患者的心理状态与卵巢储备指标之间有关系吗?

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-06-10 DOI:10.4274/tjod.galenos.2024.04248
Sakine Rahımlı Ocakoğlu, Zeliha Atak, Burak Akselim, Elif Öye, Murat Afşin Turhan, Büşra Başar Yılmaz, Emin Üstünyurt
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引用次数: 0

摘要

目的:本研究探讨了卵巢储备功能降低与不孕妇女心理状态之间的关系:本研究探讨了卵巢储备功能降低与不孕妇女心理状态之间的关系:这项横断面单中心研究的对象是 106 名不孕妇女。采用贝克抑郁量表(BDI)评估患者的抑郁倾向。记录了每位患者的不孕症相关数据,如不孕症原因、不孕症类型(原发性或继发性)、不孕症持续时间和治疗状况(既往辅助生殖技术治疗和辅助生殖技术治疗失败)。卵巢储备功能是通过实验室检测[抗苗勒氏管激素(AMH);促卵泡激素(FSH)]和经阴道超声波检查来测定每个卵巢的前卵泡数(AFC):贝克抑郁量表的总分与AFC、AMH、促甲状腺激素、FSH、雌二醇和催乳素的测量值之间无明显关系(P>0.05)。不孕原因导致的抑郁程度在各组间无明显差异(P=0.412)。此外,不孕症的类型(原发性、继发性)在组间也无差异(P=0.586)。接受过体外受精(IVF)治疗(既往有体外受精治疗失败史)的患者与未接受过体外受精治疗的患者在抑郁程度的BDI量表上没有差异:结论:AFC和AMH水平与不孕症患者的抑郁状态之间没有明显关联。
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Is there a relationship between the psychological state of infertile patient and ovarian reserve indicators?

Objective: This study explored the relationship between reduced ovarian reserve and the psychological state of infertile women.

Materials and methods: This cross-sectional, single-center study was conducted with 106 infertile women. The Beck Depression Inventory (BDI) was used to assess patients' propensity for depression. The data relating to infertility, such as causes of infertility, type of infertility (primary or secondary), duration of infertility, and treatment status [previous assisted reproductive technologies (ART) treatment and ART treatment failure] were recorded for each patient. The ovarian reserve was determined using laboratory tests [anti-Mullerian hormone (AMH); follicle-stimulating hormone (FSH)] and transvaginal ultrasonography to measure the antral follicle count (AFC) in each ovary.

Results: There was no significant relationship between the total score obtained from the Beck depression scale and AFC, AMH, thyroid-stimulating hormone, FSH, estradiol, and prolactin measurements (p>0.05). There was no significant difference between the groups regarding depression levels based on the cause of infertility (p=0.412). Additionally, the type of infertility (primary, secondary) did not differ between the groups (p=0.586). There were no differences on the BDI scale regarding the level of depression between patients who underwent in vitro fertilization (IVF) treatment (history of previous IVF treatment failure) and those who did not.

Conclusion: There was no significant association between AFC and AMH levels and the depression state of infertile patients.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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