{"title":"碱介导的正羟基苯基取代对苯醌甲酯与 CF3-亚氨酰基磺酰的正规 [4+1] 环化反应，以获得三氟乙酰亚氨酰基取代的 2,3-二氢苯并呋喃","authors":"Chen Li, Mingshuo Zhou, Zhengkai Chen","doi":"10.1016/j.jfluchem.2024.110308","DOIUrl":null,"url":null,"abstract":"<div><p>A metal-free [4 + 1] annulation of <em>ortho</em>-hydroxyphenyl substituted <em>para</em>-quinone methides (<em>p</em>-QMs) and CF<sub>3</sub>-imidoyl sulfoxonium ylides (TFISYs) has been described, producing a series of trifluoroacetimidoyl-substituted 2,3-dihydrobenzofuran derivatives in good to excellent yields with good diastereoselectivities under mild conditions.</p></div>","PeriodicalId":357,"journal":{"name":"Journal of Fluorine Chemistry","volume":"277 ","pages":"Article 110308"},"PeriodicalIF":1.7000,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Base-mediated formal [4+1] annulation of ortho-hydroxyphenyl substituted para-quinone methides and CF3-imidoyl sulfoxonium ylides to access trifluoroacetimidoyl-substituted 2,3-dihydrobenzofurans\",\"authors\":\"Chen Li, Mingshuo Zhou, Zhengkai Chen\",\"doi\":\"10.1016/j.jfluchem.2024.110308\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>A metal-free [4 + 1] annulation of <em>ortho</em>-hydroxyphenyl substituted <em>para</em>-quinone methides (<em>p</em>-QMs) and CF<sub>3</sub>-imidoyl sulfoxonium ylides (TFISYs) has been described, producing a series of trifluoroacetimidoyl-substituted 2,3-dihydrobenzofuran derivatives in good to excellent yields with good diastereoselectivities under mild conditions.</p></div>\",\"PeriodicalId\":357,\"journal\":{\"name\":\"Journal of Fluorine Chemistry\",\"volume\":\"277 \",\"pages\":\"Article 110308\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2024-06-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Fluorine Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S002211392400068X\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, INORGANIC & NUCLEAR\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Fluorine Chemistry","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S002211392400068X","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
Base-mediated formal [4+1] annulation of ortho-hydroxyphenyl substituted para-quinone methides and CF3-imidoyl sulfoxonium ylides to access trifluoroacetimidoyl-substituted 2,3-dihydrobenzofurans
A metal-free [4 + 1] annulation of ortho-hydroxyphenyl substituted para-quinone methides (p-QMs) and CF3-imidoyl sulfoxonium ylides (TFISYs) has been described, producing a series of trifluoroacetimidoyl-substituted 2,3-dihydrobenzofuran derivatives in good to excellent yields with good diastereoselectivities under mild conditions.
期刊介绍：
The Journal of Fluorine Chemistry contains reviews, original papers and short communications. The journal covers all aspects of pure and applied research on the chemistry as well as on the applications of fluorine, and of compounds or materials where fluorine exercises significant effects. This can include all chemistry research areas (inorganic, organic, organometallic, macromolecular and physical chemistry) but also includes papers on biological/biochemical related aspects of Fluorine chemistry as well as medicinal, agrochemical and pharmacological research. The Journal of Fluorine Chemistry also publishes environmental and industrial papers dealing with aspects of Fluorine chemistry on energy and material sciences. Preparative and physico-chemical investigations as well as theoretical, structural and mechanistic aspects are covered. The Journal, however, does not accept work of purely routine nature.
For reviews and special issues on particular topics of fluorine chemistry or from selected symposia, please contact the Regional Editors for further details.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
