一个不寻常的持续性合并症病例:特发性淋巴性间质性肺炎

IF 0.8 Q4 RESPIRATORY SYSTEM Respirology Case Reports Pub Date : 2024-06-10 eCollection Date: 2024-06-01 DOI:10.1002/rcr2.1408
Harriet J Caterson, Sewon Kim, Matthew Zaborowski, Michael Harden, Michael Hibbert
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引用次数: 0

摘要

淋巴细胞性间质性肺炎(LIP)是一种罕见的良性间质性肺病,最常见的病因是艾滋病和自身免疫性疾病。它很少被发现是一种特发性疾病。诊断非常复杂,需要进行大量侵入性检查,本病例就是一个很好的例子。诊断需要结合临床、放射学和组织学特征,但在我们的病例中,不寻常的放射学和临床特征意味着诊断需要外科活检。目前关于最佳治疗的证据极少,但主要涉及针对潜在病因的治疗。转化为淋巴瘤和纤维化的风险较小。使用类固醇进行免疫抑制是最常见的治疗策略,但在我们的病例中,放射学改变已自行缓解。我们介绍了一例免疫功能正常的男性病例,该病例有明显的 LIP 影像学和组织病理学发现,但无明显症状,无需干预即可自发缓解,这表明监测方法可能是一种有效的管理策略。
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An unusual case of persistent consolidation: Idiopathic lymphoid interstitial pneumonia.

Lymphocytic interstitial pneumonia (LIP) is a rare but largely benign interstitial lung disease, most frequently associated with HIV and autoimmune conditions. It is infrequently found to be an idiopathic condition. Diagnosis is complex and can require numerous invasive tests as evidenced in the case presented. The diagnosis is made from a combination of clinical, radiological, and histological features but the unusual radiological and clinical features meant diagnosis in our case required surgical biopsy. There is minimal evidence around best treatment although largely involves targeting the underlying cause. There is a small risk of transformation to lymphoma and fibrosis. Immunosuppression with steroids is the most common therapeutic strategy however in our case the radiographic changes spontaneously resolved. We present a case of an immunocompetent male presenting with significant radiological and histopathological findings of LIP, without significant symptomatology, that spontaneously resolved without intervention suggesting a monitoring approach may be a valid management strategy.

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来源期刊
Respirology Case Reports
Respirology Case Reports RESPIRATORY SYSTEM-
CiteScore
1.40
自引率
0.00%
发文量
178
审稿时长
8 weeks
期刊介绍: Respirology Case Reports is an open-access online journal dedicated to the publication of original clinical case reports, case series, clinical images and clinical videos in all fields of respiratory medicine. The Journal encourages the international exchange between clinicians and researchers of experiences in diagnosing and treating uncommon diseases or diseases with unusual presentations. All manuscripts are peer-reviewed through a streamlined process that aims at providing a rapid turnaround time from submission to publication.
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