移动用药过量应对计划:费城的流动、低门槛阿片类药物使用障碍治疗模式。

Margaret Lowenstein , Ellena Popova , Aminata Jalloh , Silvana Mazzella , Denise Botcheos , Jennifer Bertocchi , Shawn Westfahl , Kristine Pamela Garcia , Rachael Truchil , Judy Chertok
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引用次数: 0

摘要

导言:低门槛药物使用治疗项目可帮助边缘化人群克服障碍。本研究的目的是:1)描述费城一个多站点流动项目的参与者特征和治疗结果,该项目提供基于丁丙诺啡的街头初始治疗、稳定治疗和转诊至持续护理;2)研究患者特征与成功联系之间的关联:我们对 2020 年 9 月至 2021 年 12 月期间通过费城预防点的流动用药过量应对计划接受丁丙诺啡治疗的患者进行了一项回顾性队列研究。我们摘录了电子病历数据,包括患者特征、流动项目治疗和护理链接。我们使用描述性统计对样本进行了特征描述,并使用多变量逻辑回归评估了患者特征与成功护理联系之间的关联:六个地点共有 237 名患者开始使用丁丙诺啡。平均年龄为 46 岁。参与者大多为男性(67%);59%为黑人,33%为白人,15%为西班牙裔。大多数人有公共保险(74%),30%的人没有稳定住所。接受初级保健(32%)、精神治疗(5%)和心理咨询(2%)的比例较低。大多数参与者在入院时使用海洛因或芬太尼(87%),静脉注射毒品的比例较高(37%)。共用药物和之前接受过丁丙诺啡治疗的情况很普遍(73%)。86%的患者完成了≥1 次流动随访,69%的患者完成了≥4 次流动项目随访。51% 的患者至少在外部机构就诊过一次,30% 的患者在外部机构开过≥2 次丁丙诺啡处方。35%的转诊为内部转诊,即转诊至流动医疗队医生所在的大学诊所。在多变量逻辑回归模型中,内部转诊与有效护理联系的几率显著增加有关(aOR 2.31,95 % CI 1.19-4.47):结论:以低门槛药物使用护理为目标的社区外展活动促进了边缘化人群获得治疗。参与者对流动项目的参与度很高,但联系率虽然与其他低门槛模式的保留率相当,但却较低。有效联系治疗的唯一预测因素是由流动诊所医生提供的实体诊所转诊服务。这些研究结果表明,在传统医疗机构之外开展外联活动对于吸引高风险 OUD 患者参与治疗非常重要。
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The Mobile Overdose Response Program: A mobile, low-threshold opioid use disorder treatment model in Philadelphia

Introduction

Low-threshold substance use treatment programs may help overcome barriers for marginalized individuals. The aims of this study were to 1) describe participant characteristics and treatment outcomes for a multi-site, Philadelphia-based mobile program providing street-based buprenorphine initiation, stabilization, and referral to ongoing care and 2) examine associations between patient characteristics and successful linkage.

Methods

We conducted a retrospective cohort study of patients receiving buprenorphine through Prevention Point Philadelphia's mobile overdose response program from 9/2020–12/2021. We abstracted electronic medical record data, including patient characteristics, mobile program treatment, and care linkage. We used descriptive statistics to characterize the sample and assessed the association between patient characteristics and successful care linkage using multi-variable logistic regression.

Results

Two hundred thirty-seven patients initiated buprenorphine in the program across six sites. Mean age was 46. Participants were majority men (67 %); 59 % identified as Black, 33 % identified as White, and 15 % reported Hispanic ethnicity. Most were publicly insured (74 %) and 30 % were unstably housed. Basedline engagement in primary care (32 %), psychiatric treatment (5 %), and counseling (2 %) were low. Most participants reported heroin or fentanyl use at intake (87 %), with high rates of IV drug use (37 %)., and co-occurring substance use and prior buprenorphine treatment experience were common.. 86 % completed ≥1 mobile follow-up visit, and 69 % completed ≥4 mobile program visits. 51 % of patients attended at least one visit at an outside site, and 30 % had ≥2 visits for buprenorphine prescriptions at an outside site. 35 % of the referrals were internal, meaning they went to University-based practices staffed by the mobile unit physicians. In a multivariable logistic regression model, internal referral was associated with significantly increased odds of effective care linkage (aOR 2.47, 95 % CI 1.20–5.09).

Conclusions

Targeted community outreach with low-threshold substance use care facilitated treatment access among marginalized individuals. Participants showed high levels of engagement with the mobile program, but rates of outside care linkage, while comparable to retention in other low-threshold models, were lower. The only predictor of effective care linkage was referral to brick-and-mortar clinics staffed by mobile unit physicians. These findings support the importance of outreach beyond traditional health care settings to engage high-risk patients with OUD.

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来源期刊
Journal of substance use and addiction treatment
Journal of substance use and addiction treatment Biological Psychiatry, Neuroscience (General), Psychiatry and Mental Health, Psychology (General)
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