新诊断的 2 型糖尿病酮症酸中毒患者之前饮用含糖饮料与糖尿病缓解之间的关系。

IF 1.3 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Endocrine journal Pub Date : 2024-09-02 Epub Date: 2024-06-12 DOI:10.1507/endocrj.EJ24-0042
Shanshan Li, Jinying Wang, Junping Zhang, Yun Zou, Yuanyuan Deng, Jixiong Xu
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引用次数: 0

摘要

本研究探讨了过量摄入含糖饮料(SSB)与随后的糖尿病缓解率(DR)之间的潜在相关性。研究招募了 206 名在 2019 年 1 月至 2022 年 6 月期间符合资格标准的人。研究人员对参与者在发病前的饮料消费情况进行了调查。随后,根据参与者是否符合糖尿病缓解的诊断标准,将其分为糖尿病缓解组(DR 组)和非糖尿病缓解组(NDR 组)。将两组的基线临床要素并列,并通过逻辑回归分析确定影响糖尿病缓解的因素。根据接收者操作特征曲线确定了各关键因素的临界值。有 109 名患者报告有饮用固体饮料的历史,而其余 58 名患者则没有此类历史。一年后,40 名患者的糖尿病得到缓解。与 NDR 组相比,DR 组的 SSBs 比率、体重指数 (BMI) 和血肌酐 (BCr) 均高于 NDR 组,调整混杂因素后,SSBs(几率比 [OR] = 3.503;95% 置信区间 [CI] = 1.334-9.202;P = 0.011)和 BCr(OR = 1.038;95% CI = 1.003-1.079;P = 0.042)成为 DR 的独立预测因素。SSB 和 BCr 的综合指数可有效预测 DR(ROC 曲线下面积 [AUC] = 0.810,p < 0.001)。SSBs和BCr是DR的独立风险因素。将这些标记物结合在一起可以更准确地预测 DR。
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Association between previous consumption of sugar-sweetened beverages and diabetes remission in patients with newly diagnosed type 2 diabetic ketoacidosis.

This study examined the potential correlation between the immoderate intake of sugar-sweetened beverages (SSBs) and the subsequent rate of diabetes remission (DR). 206 individuals who met the eligibility criteria between January 2019 and June 2022 were recruited. Inquiries were conducted to gather information on the participants' beverage consumption before the onset. Subsequently, the participants were separated into the diabetes remission group (DR group) and nondiabetes remission group (NDR group) depending on whether they met the diagnostic criteria for diabetes remission. Baseline clinical elements within the two groups were juxtaposed, and factors influencing diabetes remission were identified through logistic regression analyses. The cutoff values of each critical factor were determined based on the receiver operating characteristic curve. One hundred and nine patients reported a history of SSB consumption, while the remaining 58 reported no such history. After 1 year, 40 patients achieved remission from diabetes. Compared with the NDR group, a higher SSBs ratio, body mass index (BMI), and blood creatinine (BCr) was observed in the DR group after adjusting for confounders, SSBs (odds ratio [OR] = 3.503; 95% confidence interval [CI] = 1.334-9.202; p = 0.011) and BCr (OR = 1.038; 95% CI = 1.003-1.079; p = 0.042) emerged as independent predictors of DR. The composite index of SSBs and BCr efficaciously predicted DR (area under the ROC curve [AUC] = 0.810, p < 0.001). SSBs and BCr were independent risk factors for DR. The amalgamation of these markers could more accurately predict DR.

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来源期刊
Endocrine journal
Endocrine journal 医学-内分泌学与代谢
CiteScore
4.30
自引率
5.00%
发文量
224
审稿时长
1.5 months
期刊介绍: Endocrine Journal is an open access, peer-reviewed online journal with a long history. This journal publishes peer-reviewed research articles in multifaceted fields of basic, translational and clinical endocrinology. Endocrine Journal provides a chance to exchange your ideas, concepts and scientific observations in any area of recent endocrinology. Manuscripts may be submitted as Original Articles, Notes, Rapid Communications or Review Articles. We have a rapid reviewing and editorial decision system and pay a special attention to our quick, truly scientific and frequently-citable publication. Please go through the link for author guideline.
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