原发性减肥手术联合其他手术的全球 30 天发病率和死亡率:BLEND 研究。

IF 2.9 3区 医学 Q1 SURGERY Obesity Surgery Pub Date : 2024-11-01 Epub Date: 2024-06-13 DOI:10.1007/s11695-024-07296-0
Alessandro Martinino, Kushan D L Nanayakkara, Brij Madhok, Geoffrey Yuet Mun Wong, Mohamed Abouelazayem, Juan Pablo Scarano Pereira, Ishaan Wazir, Vignesh Balasubaramaniam, Amira Said, Cláudia Marques, Amr Abdelbaeth, Khayry Al-Shami, Muna Albashari, Akram Alkaseek, Mohammad Abdullah Almayouf, Mohammad Aloulou, Awadh Robaan Alqahtan, Alan Askari, Meena Faiez Assad Attia, Ahmed K Awad, Muhammed Rasid Aykota, Nicolae Bacalbasa, Francisco J Barrera-Rodriguez, Domenico Benavoli, Srikar Billa, Vincenzo Borrelli, İsmail Çalıkoğlu, Michela Campanelli, Miguel A Carbajo, Sharfuddin Chowdhury, Luca Cristin, Giovanni Dapri, Zhiyong Dong, Mohamad Hayssam Elfawal, Amr Elgazar, Muhammed Elhadi, Paolo Gentileschi, Yitka Graham, Bassel Haj, Joseph Andrew Johnson, Abd-Elfattah Morsi Kalmoush, Ayman Kamal, Anna Kamocka, Almu'atasim Khamees, Giorgio Lisi, Edgard Efren Lozada Hernandez, Giuseppe M Marinari, Gennaro Martines, Serhat Meric, Fernando Mier, Ahmed Mohamed Ali, Diyaaldeen Mohammed, Karim Mostafa Mohamed, Francesk Mulita, Mario Musella, William Edward O'Malley, Stefano Olmi, Taryel Omarov, Omnya Osama, HMinali R Perera, Giovanni Piscitelli, Tigran Poghosyan, David Ramírez, Masoud Rezvani, Rui Ribeiro, Aaron Sabbota, Nasser Sakran, Khaled Ahmad Sawaftah, Kaci Schiavone, Ozan Şen, Maria Sotiropoulou, Nicola Tartaglia, Merve Tokocin, Manuela Trotta, Ahmet Gökhan Türkçapar, Matteo Uccelli, Cesar Vargas, Georgios -Ioannis Verras, Cunchuan Wang, Zhuoqi Wei, Wah Yang, Carlos Zerrweck, Eloise Owen, Georgios V Gkoutos, Victor Roth Cardoso, Rishi Singhal, Kamal Mahawar
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引用次数: 0

摘要

背景:目前还没有关于单纯初级减肥和代谢手术(BMS)与初级BMS联合其他手术安全性的可靠数据:本研究的目的是收集初级 BMS 与胆囊切除术、腹股沟疝修补术或食管裂孔疝修补术相结合的 30 天死亡率和发病率:这是一项国际性、多中心、前瞻性和观察性审计,审计对象是接受初级 BMS 并同时接受一种或多种附加手术的患者:审计时间为 2022 年 1 月 1 日至 6 月 30 日。进行了描述性分析。倾向得分匹配分析将BLEND研究的患者与GENEVA队列的患者进行比较,以客观评估联合手术与单纯初治BMS的效果:共有 75 个中心提交了 1036 名患者的数据。袖带胃切除术是最常见的主要 BMS(N = 653,63%),食管裂孔疝修补术是最常见的并发症(N = 447,43.1%)。在 30 天的发病率中,RYGB 占比最高(20.6%),其次是 SG(10.5%)。在所有合并手术中,一种以上合并手术的发病率最高(17.1%)。在所有134例并发症中,129例(96.2%)为Clavien-Dindo I-III期并发症,4例为CD V期并发症。与仅接受BMS手术的患者相比,接受初级减肥手术并同时接受其他手术的患者30天并发症发生率明显增加(12.7% vs. 7.1%):结论:将 BMS 与其他手术合并会增加并发症的风险,但大多数并发症都很轻微,无需进一步治疗。对于经过多学科讨论后选定的患者来说,与主BMS联合手术是一个可行的选择。
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Global 30-Day Morbidity and Mortality of Primary Bariatric Surgery Combined with Another Procedure: The BLEND Study.

Background: No robust data are available on the safety of primary bariatric and metabolic surgery (BMS) alone compared to primary BMS combined with other procedures.

Objectives: The objective of this study is to collect a 30-day mortality and morbidity of primary BMS combined with cholecystectomy, ventral hernia repair, or hiatal hernia repair.

Setting: This is as an international, multicenter, prospective, and observational audit of patients undergoing primary BMS combined with one or more additional procedures.

Methods: The audit took place from January 1 to June 30, 2022. A descriptive analysis was conducted. A propensity score matching analysis compared the BLEND study patients with those from the GENEVA cohort to obtain objective evaluation between combined procedures and primary BMS alone.

Results: A total of 75 centers submitted data on 1036 patients. Sleeve gastrectomy was the most commonly primary BMS (N = 653, 63%), and hiatal hernia repair was the most commonly concomitant procedure (N = 447, 43.1%). RYGB accounted for the highest percentage (20.6%) of a 30-day morbidity, followed by SG (10.5%). More than one combined procedures had the highest morbidities among all combinations (17.1%). Out of overall 134 complications, 129 (96.2%) were Clavien-Dindo I-III, and 4 were CD V. Patients who underwent a primary bariatric surgery combined with another procedure had a pronounced increase in a 30-day complication rate compared with patients who underwent only BMS (12.7% vs. 7.1%).

Conclusion: Combining BMS with another procedure increases the risk of complications, but most are minor and require no further treatment. Combined procedures with primary BMS is a viable option to consider in selected patients following multi-disciplinary discussion.

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来源期刊
Obesity Surgery
Obesity Surgery 医学-外科
CiteScore
5.80
自引率
24.10%
发文量
567
审稿时长
3-6 weeks
期刊介绍: Obesity Surgery is the official journal of the International Federation for the Surgery of Obesity and metabolic disorders (IFSO). A journal for bariatric/metabolic surgeons, Obesity Surgery provides an international, interdisciplinary forum for communicating the latest research, surgical and laparoscopic techniques, for treatment of massive obesity and metabolic disorders. Topics covered include original research, clinical reports, current status, guidelines, historical notes, invited commentaries, letters to the editor, medicolegal issues, meeting abstracts, modern surgery/technical innovations, new concepts, reviews, scholarly presentations and opinions. Obesity Surgery benefits surgeons performing obesity/metabolic surgery, general surgeons and surgical residents, endoscopists, anesthetists, support staff, nurses, dietitians, psychiatrists, psychologists, plastic surgeons, internists including endocrinologists and diabetologists, nutritional scientists, and those dealing with eating disorders.
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