显示坏死病灶空间分布的全景热图。

IF 4.7 2区 医学 Q2 CELL & TISSUE ENGINEERING Bone & Joint Research Pub Date : 2024-06-17 DOI:10.1302/2046-3758.136.BJR-2023-0181.R2
Peng Yang, Wei He, Weiming Yang, Luoyong Jiang, Tianye Lin, Weichao Sun, Qingwen Zhang, Xueling Bai, Da Guo, Wei Sun
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引用次数: 0

摘要

目的:在本研究中,我们旨在使用一种新的测量方法直观显示股骨头坏死的空间分布特征:我们回顾性地收集了两个临床中心的 76 名连续患者(平均年龄 34.3 岁(SD 8.1),56.58% 为男性(n = 43))的 108 个非创伤性股骨头坏死髋关节的 CT 影像数据。采用一种名为经纬度分割系统(LLDS)的新测量系统,将股骨头分为 288 个标准单位(根据单位在股骨头内的方位,分别命名为 N[上]、S[下]、E[前]和 W[后])。此外,还开发了一种计算机辅助设计(CAD)测量工具,用于可视化测量 CT 图像中坏死病灶的空间位置。两名骨科医生独立进行测量,测量结果用于绘制股骨头坏死病灶空间分布的二维和三维热图,并进行统计分析:结果:结果表明,LLDS的评分间可靠性很高。热图显示,日本调查委员会(JIC)分类的C型坏死病灶的分布呈现集群特征,病灶集中在北部和东部地区,形成了以外环区块N4-N6E2、N3-N6E单元为中心的热区(90%概率)。统计结果表明,C2 型和 C1 型的分布差异在 E1 和 E2 单元最为显著,结合热图,表明 N3-N6E1 和 N1-N3E2 单元的空间分布差异对于了解 C1 和 C2 型坏死病变至关重要:结论:LLDS 可用于准确测量坏死病灶的空间位置并显示其分布特征。
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Panoramic heat map for spatial distribution of necrotic lesions.

Aims: In this study, we aimed to visualize the spatial distribution characteristics of femoral head necrosis using a novel measurement method.

Methods: We retrospectively collected CT imaging data of 108 hips with non-traumatic osteonecrosis of the femoral head from 76 consecutive patients (mean age 34.3 years (SD 8.1), 56.58% male (n = 43)) in two clinical centres. The femoral head was divided into 288 standard units (based on the orientation of units within the femoral head, designated as N[Superior], S[Inferior], E[Anterior], and W[Posterior]) using a new measurement system called the longitude and latitude division system (LLDS). A computer-aided design (CAD) measurement tool was also developed to visualize the measurement of the spatial location of necrotic lesions in CT images. Two orthopaedic surgeons independently performed measurements, and the results were used to draw 2D and 3D heat maps of spatial distribution of necrotic lesions in the femoral head, and for statistical analysis.

Results: The results showed that the LLDS has high inter-rater reliability. As illustrated by the heat map, the distribution of Japanese Investigation Committee (JIC) classification type C necrotic lesions exhibited clustering characteristics, with the lesions being concentrated in the northern and eastern regions, forming a hot zone (90% probability) centred on the N4-N6E2, N3-N6E units of outer ring blocks. Statistical results showed that the distribution difference between type C2 and type C1 was most significant in the E1 and E2 units and, combined with the heat map, indicated that the spatial distribution differences at N3-N6E1 and N1-N3E2 units are crucial in understanding type C1 and C2 necrotic lesions.

Conclusion: The LLDS can be used to accurately measure the spatial location of necrotic lesions and display their distribution characteristics.

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来源期刊
Bone & Joint Research
Bone & Joint Research CELL & TISSUE ENGINEERING-ORTHOPEDICS
CiteScore
7.40
自引率
23.90%
发文量
156
审稿时长
12 weeks
期刊介绍: The gold open access journal for the musculoskeletal sciences. Included in PubMed and available in PubMed Central.
期刊最新文献
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