涉及二氧化硫插入的肼的直接 C-H 磺化反应

IF 4.6 1区化学 Q1 CHEMISTRY, ORGANIC Organic Chemistry Frontiers Pub Date : 2024-06-17 DOI:10.1039/D4QO00835A

Mengzhao Yu, Shuizhen Lin, Shuoshuo Zhang, Xinkui Lin and Xiaolei Huang

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引用次数: 0

摘要

本文介绍了醛基肼与 DABSO 和芳基偶氮四氟硼酸盐的三组分反应。通过使用有机 DABSO 作为 SO2 的来源，这种直接的磺酰化方法为中等至极好收率的 (E)-sufonylated 肼酮提供了一个优雅的途径。此外，利用磺酰氯作为活性磺化试剂，还可以在光催化条件下实现肼的磺化反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Direct C–H sulfonylation of hydrazones involving the insertion of SO2†

A three-component reaction of aldehyde-derived hydrazones with DABSO and aryldiazonium tetrafluoroborates is described. By using organic DABSO as the source of SO₂, this straightforward sulfonylation tactic provides an elegant access to (E)-sulfonylated hydrazones in moderate to excellent yields. Moreover, the sulfonylation of hydrazones can also be achieved under photocatalyzed conditions by using sulfonyl chlorides as the active sulfonylating reagents.

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来源期刊

Organic Chemistry Frontiers CHEMISTRY, ORGANIC-

CiteScore

7.90

自引率

11.10%

发文量

686

审稿时长

1 months

期刊介绍： Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.