诊断乳腺癌的实验室检验

Salena Abdul Abbas Naser, Mohammed Abdulrazzaq Assi, Shahad Saad Mohammed, Ali Al-Fahham
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摘要

乳腺癌(BC)已对全球妇女的总体健康构成重大威胁,其发病率和死亡率在中国随着时间的推移呈明显上升趋势。研究表明,早期乳腺癌患者的生存率明显高于中晚期患者。因此,重视乳腺癌快速诊断的研究至关重要。迄今为止,已经开发出许多诊断方法,主要是利用成像和分子生物技术。这些方法极大地促进了乳腺癌的诊断和随访。本综述文章简要介绍了最近用于诊断乳腺癌的主要实验室方法。文章总结说,目前已开发出许多诊断方法,用于在肿瘤的不同阶段检测乳腺癌。其中一些检测方法用于确定适当的化疗方法(如基因变化的分子检测),其他检测方法则更多地用于确定多种肿瘤(如全血细胞计数),而唾液检测方法在诊断乳腺癌方面仍存在争议。
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Laboratory Tests For The Diagnosis Of Breast Cancer
Breast cancer (BC) has posed a significant threat to the general health of women globally, with its incidence and mortality rates showing a noticeable increase in China over time. Research indicates that the survival rate for early-stage breast cancer patients is significantly higher compared to those diagnosed at middle or late stages. Therefore, it is crucial to focus on research for the rapid diagnosis of breast cancer. Numerous diagnostic methods have been developed to date, primarily utilizing imaging and molecular biotechnology. These methods have greatly contributed to the diagnosis and follow up of BC. In this review article, a brief explanation has been introduced about the main laboratory methods that are recently used in the diagnosis of BC. It has been concluded that many diagnostic methods have been developed to detect breast cancer at different stages of the tumor. Some of these tests have been used to determine the appropriate chemotherapy method (e.g. molecular tests for gene changes), other are more generic in the determination of many tumor (e.g. complete blood count), while salivary methods are still controversial in the diagnosis of BC.
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