Isolation of stilbenoids from fresh knotwood of Scots pine using a high yield method

Abstract Scots pine knotwood contains valuable amount of stilbenoids such as pinosylvin (Ps) and pinosylvin monomethyl ether (PsMME). The stilbenoids have numerous biological activities. Traditional methods of extracting stilbenoids often yield low quantities and involve complex processes. In the present study, a simple and high-yield method was proposed for the extraction of stilbenoids from fresh Scots pine knotwood using ethanol taking a total of three days. In addition, the impact of drying process, extraction time, extraction solvents (acetone and ethanol) and storage time were evaluated on the yield of the stilbenoids. The increased yield and improved extraction efficiency make this method a promising advancement for promoting the utilization of stilbenoids for their valuable bioactive properties.