一名患有严重 COVID-19、艾滋病、心血管受损和既往肺部感染的患者因多器官衰竭而死亡

Francisco Medros Junior, Priscila Oliveira de Souza, Juliana Eymara Fernandes Barbosa de Paula, Mauricea Francisco da Silva Romero Gonzalez, Cristiane Gomes da Silva, D. F. Barreto-Vieira, Derick Mendes Bandeira
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摘要

目的报告一例 SARS-CoV-2/HIV 合并感染病例,患者近期有肺部感染病史,在住院接受 COVID-19 治疗当天心肺功能骤停,多器官功能衰竭数日后死亡。病例详情:一名 33 岁的免疫抑制男性患者(放弃艾滋病毒治疗)因呼吸道症状被送入急诊科,经检测,SARS-CoV-2 病毒呈阳性。住院期间,患者心跳呼吸骤停,并出现了严重的炎症、真菌感染、败血症、代谢性酸中毒、动脉高血压、血栓形成、出血以及肝、肌肉和肾损伤。最后,他出现多器官衰竭,最终死亡。结论艾滋病病毒引起的严重免疫抑制,加上潜在的心肺疾病,是导致 COVID-19 死亡的原因。
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Death due to multiple organ failure in a patient with severe COVID-19, AIDS, cardiovascular impairment, and previous lung infections
Objective: To report a case of SARS-CoV-2/HIV coinfection in a patient with a history of recent lung infections who had a cardiopulmonary arrest on the day of hospitalization for COVID-19 treatment, dying some days after multiple organ failure. Case detail: A 33-year-old immunosuppressed male patient (abandoning treatment for HIV) was admitted to the emergency department with respiratory symptoms and tested positive for SARS-CoV-2. During hospitalization, the patient had a cardiorespiratory arrest and presented a robust inflammatory profile, fungal infection, sepsis, metabolic acidosis, arterial hypertension, thrombosis, hemorrhage, and hepatic, muscular, and renal injury. Finally, he evolved with multiple organ failures, leading to death. Conclusion: Severe immunosuppression caused by HIV, associated with underlying cardiopulmonary diseases, contributes to lethal outcomes of COVID-19.
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