Jia-Qiang Wu, Wei Lin, Yifei Qu, Mei Xie, Huixuan Zhu, Jinhui Hu, Zhuang Xiong, Jun Xu, Wenhua Chen
{"title":"Rh(III)催化的苯甲酰胺氧化还原中性 C-H 多氟烯化反应","authors":"Jia-Qiang Wu, Wei Lin, Yifei Qu, Mei Xie, Huixuan Zhu, Jinhui Hu, Zhuang Xiong, Jun Xu, Wenhua Chen","doi":"10.1055/a-2343-0676","DOIUrl":null,"url":null,"abstract":"Fluorinated molecules are widely used in pharmaceutical and agrochemical industries. Multifluoroalkyl-containing compounds have attracted increasing attention for their unique ability to alter the activity of drugs and bioactive molecules. Herein, we report an efficient Rh(III)-catalyzed redox-neutral C-H multifluoroalkenylation of benzamides with multifluoroalkenes, which provides a versatile protocol for accessing a wide range of multifluoroalkenylated arenes.","PeriodicalId":501298,"journal":{"name":"Synthesis","volume":"38 14","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Rh(III)-Catalyzed Redox-neutral C-H Multifluoroalkenylation of Benzamides\",\"authors\":\"Jia-Qiang Wu, Wei Lin, Yifei Qu, Mei Xie, Huixuan Zhu, Jinhui Hu, Zhuang Xiong, Jun Xu, Wenhua Chen\",\"doi\":\"10.1055/a-2343-0676\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Fluorinated molecules are widely used in pharmaceutical and agrochemical industries. Multifluoroalkyl-containing compounds have attracted increasing attention for their unique ability to alter the activity of drugs and bioactive molecules. Herein, we report an efficient Rh(III)-catalyzed redox-neutral C-H multifluoroalkenylation of benzamides with multifluoroalkenes, which provides a versatile protocol for accessing a wide range of multifluoroalkenylated arenes.\",\"PeriodicalId\":501298,\"journal\":{\"name\":\"Synthesis\",\"volume\":\"38 14\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-06-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Synthesis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1055/a-2343-0676\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Synthesis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/a-2343-0676","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Rh(III)-Catalyzed Redox-neutral C-H Multifluoroalkenylation of Benzamides
Fluorinated molecules are widely used in pharmaceutical and agrochemical industries. Multifluoroalkyl-containing compounds have attracted increasing attention for their unique ability to alter the activity of drugs and bioactive molecules. Herein, we report an efficient Rh(III)-catalyzed redox-neutral C-H multifluoroalkenylation of benzamides with multifluoroalkenes, which provides a versatile protocol for accessing a wide range of multifluoroalkenylated arenes.