用于检测食物毒素的免疫传感器发展新趋势

F. Nsanzabera, Aimable Mwiseneza, Evangeline Irakoze, John Bosco Nsengiyumva, Barthazar Nduwayezu, Alexis Manishimwe, Fabien Nkurikiyimana
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摘要

本研究强调了食源性疾病对公众健康的持续威胁,主要是由细菌病原体引起的。传统的微生物检测技术灵敏但耗时,尽管取得了进步,但要确保在整个食品供应链中及时发现污染物仍面临挑战。危害分析关键控制点(HACCP)系统被认为是确保食品安全的更有效方法,它强调在生产的关键点主动识别和控制危害。定量聚合酶链反应 (PCR) 和生物传感器等新兴技术提供了更快、更准确的检测方法,但也有一定的局限性。尤其是 ELISA、SPR 和电化学免疫传感器等生物传感器,因其灵敏度高、特异性强,可快速检测多种污染物而大有可为。本文强调了将先进技术与既定食品安全规程相结合以提高食品安全和质量的重要性,从而使消费者、生产商和监管机构共同受益。
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Emerging Trends of Immunosensors Development for Detection of Food Toxins
The present study highlights the ongoing threat of foodborne illnesses to public health, primarily caused by bacterial pathogens. Despite advancements in conventional microbiological testing techniques, which are sensitive but time-consuming, challenges remain in ensuring timely detection of contaminants throughout the food supply chain. The Hazard Analysis Critical Control Point (HACCP) system is recognized as a more effective approach to ensuring food safety, emphasizing proactive identification and control of hazards at critical points in production. Emerging technologies like quantitative polymerase chain reaction (PCR) and biosensors offer faster and more accurate detection methods, although with certain limitations. Biosensors such as ELISA, SPR, and electrochemical immunosensors, in particular, show promise due to their high sensitivity and specificity, enabling rapid detection of a wide range of contaminants. This paper underscores the importance of integrating advanced technologies with established food safety protocols to enhance the safety and quality of food products, benefiting consumers, producers, and regulatory agencies alike.
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