S. Khayat, H. Fanaei, Farideh Riki, Shahindokht Navabi Rigi, Ebrahim Alijani
{"title":"吸食鸦片对产后脐带血和产妇血液中炎症因子的影响:新生儿并发症的潜在诱因","authors":"S. Khayat, H. Fanaei, Farideh Riki, Shahindokht Navabi Rigi, Ebrahim Alijani","doi":"10.1177/00220426241259374","DOIUrl":null,"url":null,"abstract":"Opium addiction during pregnancy can have significant effects on the activity of the immune system as well as on pregnancy outcomes. A study was conducted comparing opium-addicted pregnant women to healthy pregnant women. Blood samples were taken from the maternal vein and umbilical cord immediately after delivery to measure concentrations of inflammatory markers. The results showed that the opium-addicted group had significantly higher levels of IL-6, IL-10, CRP, C3, and C4 in both maternal and cord blood samples compared to the control group. Additionally, adverse pregnancy outcomes such as NICU admissions, neonatal deaths, and low Apgar scores were more prevalent in the opium-addicted group. These findings suggest that opium addiction during pregnancy can lead to postpartum inflammation and negatively impact pregnancy outcomes. It is important to address opium addiction and provide appropriate support and treatment to pregnant women to improve pregnancy outcomes and reduce the risk of complications.","PeriodicalId":15626,"journal":{"name":"Journal of Drug Issues","volume":null,"pages":null},"PeriodicalIF":1.2000,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Impact of Opium Consumption on Inflammatory Factors in Umbilical Cord Blood and Maternal Blood Postpartum: A Potential Contributor to Neonatal Complications\",\"authors\":\"S. Khayat, H. Fanaei, Farideh Riki, Shahindokht Navabi Rigi, Ebrahim Alijani\",\"doi\":\"10.1177/00220426241259374\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Opium addiction during pregnancy can have significant effects on the activity of the immune system as well as on pregnancy outcomes. A study was conducted comparing opium-addicted pregnant women to healthy pregnant women. Blood samples were taken from the maternal vein and umbilical cord immediately after delivery to measure concentrations of inflammatory markers. The results showed that the opium-addicted group had significantly higher levels of IL-6, IL-10, CRP, C3, and C4 in both maternal and cord blood samples compared to the control group. Additionally, adverse pregnancy outcomes such as NICU admissions, neonatal deaths, and low Apgar scores were more prevalent in the opium-addicted group. These findings suggest that opium addiction during pregnancy can lead to postpartum inflammation and negatively impact pregnancy outcomes. It is important to address opium addiction and provide appropriate support and treatment to pregnant women to improve pregnancy outcomes and reduce the risk of complications.\",\"PeriodicalId\":15626,\"journal\":{\"name\":\"Journal of Drug Issues\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2024-06-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Drug Issues\",\"FirstCategoryId\":\"90\",\"ListUrlMain\":\"https://doi.org/10.1177/00220426241259374\",\"RegionNum\":4,\"RegionCategory\":\"社会学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"SUBSTANCE ABUSE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Drug Issues","FirstCategoryId":"90","ListUrlMain":"https://doi.org/10.1177/00220426241259374","RegionNum":4,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"SUBSTANCE ABUSE","Score":null,"Total":0}
The Impact of Opium Consumption on Inflammatory Factors in Umbilical Cord Blood and Maternal Blood Postpartum: A Potential Contributor to Neonatal Complications
Opium addiction during pregnancy can have significant effects on the activity of the immune system as well as on pregnancy outcomes. A study was conducted comparing opium-addicted pregnant women to healthy pregnant women. Blood samples were taken from the maternal vein and umbilical cord immediately after delivery to measure concentrations of inflammatory markers. The results showed that the opium-addicted group had significantly higher levels of IL-6, IL-10, CRP, C3, and C4 in both maternal and cord blood samples compared to the control group. Additionally, adverse pregnancy outcomes such as NICU admissions, neonatal deaths, and low Apgar scores were more prevalent in the opium-addicted group. These findings suggest that opium addiction during pregnancy can lead to postpartum inflammation and negatively impact pregnancy outcomes. It is important to address opium addiction and provide appropriate support and treatment to pregnant women to improve pregnancy outcomes and reduce the risk of complications.
期刊介绍:
The Journal of Drug Issues (JDI) was incorporated as a nonprofit entity in the State of Florida in 1971. In 1996, JDI was transferred to the Florida State University College of Criminology and Criminal Justice, and the Richard L. Rachin Endowment was established to support its continued publication. Since its inception, JDI has been dedicated to providing a professional and scholarly forum centered on the national and international problems associated with drugs, especially illicit drugs. It is a refereed publication with international contributors and subscribers. As a leader in its field, JDI is an instrument widely used by research scholars, public policy analysts, and those involved in the day-to-day struggle against the problem of drug abuse.