保加利亚初级医疗保健中的甲状腺病理超声筛查

Anabela Glavanova, Branimir Raduilov, Tsvetelina V. Miteva, Mariela Kamburova, Ivan Polyakov, E. Mekov
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摘要

甲状腺疾病是一种常见病,在大多数情况下,可在初级医疗机构得到安全有效的检测和治疗。本文旨在分析和评估保加利亚初级医疗机构的甲状腺超声波异常率。研究时间为2016年至2021年。研究对象包括接受年度预防性筛查的随机队列患者。研究人员收集了人口统计学信息(年龄和性别)。根据以下参数对超声波检查结果的描述进行了标准化:甲状腺的形状、大小和位置偏差,实质回声与正常回声的偏差(高回声、低回声和异回声实质),可检测到的形成的存在和大小,以及钙化的存在。这项研究的总参与人数为 3 178 人。其中,60%(1 907/3 178)为女性,40%(1 271/3 178)为男性。参与者的平均年龄为 40.1 ± 11.3 岁,男女之间无明显差异。36.2%(1 151/3 178)的超声波检查结果与正常值有偏差,随着年龄的增长,出现偏差的频率也在增加。19.7%的患者(625/3 178)出现了可检测到的肿块,大于 1 厘米的肿块占所有病例的 4.4%(139/3 178),占所有肿块的 22.2%(139/625)。发现钙化的比例为0.5%(15/3 163)。超过1/3的甲状腺超声检查结果显示异常。与男性相比,女性甲状腺超声波异常的发生率明显更高,而且其发生率随年龄的增长而增加。
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Ultrasound screening of thyroid pathology in primary medical care in Bulgaria
Thyroid diseases are common and, in most cases, can be safely and effectively detected and treated in primary medical care. This article aimed to analyze and evaluate the rate of thyroid ultrasonographic abnormalities in a primary medical care practice in Bulgaria. The research was conducted from 2016 to 2021. A random cohort of patients undergone annual preventive screening was included. Demographic information (age and sex) was collected. The descriptions of the ultrasonographic findings were standardized based on the following parameters: deviations in shape, size, position of the thyroid gland, deviations from normal parenchymal echogenicity (hyper-, hypo-, and heteroechogenic parenchyma), presence and size of detectable formations, and presence of calcifications. The total number of participants in this study was 3 178. Of these, 60% (1 907/3 178) were women and 40% (1 271/3 178) were men. The average age of participants was 40.1 ± 11.3 years, and there was no significant difference between the males and females. Deviations from normal ultrasonographic findings were observed in 36.2% (1 151/3 178), with a frequency increasing with age. Detectable formations were seen in 19.7% (625/3 178) of the patients, and those larger than 1 cm accounted for 4.4% (139/3 178) of all cases and 22.2% of all formations (139/625). Calcifications were found in 0.5% (15/3 163). Over 1/3 of the performed thyroid ultrasounds revealed abnormalities. Thyroid ultrasonographic abnormalities were significantly more common in women compared to men, and their frequency increased with age.
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