关于影响儿童肾病患病率的一些因素的研究

E. A. Muhsin, Shahrazad A. Khalaf, A. Abdulkareem
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摘要

本研究于 2023 年 11 月 1 日至 25 日进行。研究对象包括 62 名年龄在(1-12)岁之间的男女儿童患者:26 名慢性肾功能衰竭儿童患者和 36 名肾病综合征儿童患者,他们都是伊拉克巴格达 Al-Mansour 儿科教学医院和儿童中心教学医院肾病科和透析科的门诊和住院患者。对照组由 26 名儿童组成,年龄范围与男女患者组相同。采集了患者和对照组的血液样本。然后通过实验室检测对肾功能进行评估,除了血型和 Rh 因子检测外,还测量了血清中的尿素和肌酐水平。记录了可能影响肾病发病率和进展的因素,如社会经济地位、居住地(北部、中部和南部)和家族史。结果表明,与对照组相比,血清中尿素和肌酐的浓度均明显升高(P<0.001)。两组患儿的血型和Rh因子无明显差异。在本次研究中,所有受影响因素与肾病的发病率和进展均无明显关联。每个儿童患者的年龄和性别对肾病类型没有明显影响(P 值≤ 0.01)。
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A study of Some Factors Affecting the Prevalence of Renal Disease in Children
The current study was carried out in the period from 1 to 25 November 2023. It included sixty-two pediatric patients in the age range of (1-12) years and male and female children: twenty-six pediatric patients with chronic renal failure and thirty-six pediatric patients with nephrotic syndrome, who were outpatients and inpatients in the renal diseases unit and dialysis unit of both Al-Mansour Pediatric Teaching Hospital and Child's Central Teaching Hospital in Baghdad, Iraq. The control group consisted of twenty-six children in the same age range as the sick groups of males and females. Blood samples were collected from patients and controls. Then renal function was evaluated by applying the laboratory tests as urea and creatinine levels were measured in serum, besides blood group and Rh factor tests. Factors that may affect renal disease incidence and progress were recorded, such as socioeconomic status, residence (North, Middle, and South), and family history. The results explained the significant increase in both urea and creatinine concentrations (P<0.001) in serum compared with controls. The blood group and Rh factor had no significant differences among children of both sick groups. The entire affected factors had no significant association with renal disease incidence or progress in the current study. The age and gender of each child patient had no significant effect on the type of renal disease (at P value ≤ 0.01).
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