用于脱氧核糖核酸检测的高灵敏度石墨烯基等离子结构

IF 2.1 4区 物理与天体物理 Q2 OPTICS Photonics Pub Date : 2024-06-09 DOI:10.3390/photonics11060549
Z. Salehnezhad, M. Soroosh, Haraprasad Mondal
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引用次数: 0

摘要

本研究设计了一种具有石墨烯-WS2 混合层的 Kretschmann 结构,用于开发一种灵敏的脱氧核糖核酸检测生物传感器。该生物传感器以 45 纳米的金层作为活性层,以铬薄膜作为粘合层。通过优化石墨烯层和 WS2 层,再加上硅层,我们可以提高纳米传感器的灵敏度。薄薄的硅层既是金属的保护屏障,又增加了相互作用的体积。因此,通过调整活性金属的厚度和添加硅层,我们可以获得更高的灵敏度和更低的半最大全宽,从而使灵敏度达到 333.33°/RIU。利用数值技术和有限差分时域法分析了所设计的结构,从而获得了表面等离子体极化子传感器的光学特性。通过计算和评估各种参数,确定了传感器的最佳条件。此外,传感器的总尺寸为 2.228 µm2。
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A Highly Sensitive Plasmonic Graphene-Based Structure for Deoxyribonucleic Acid Detection
In this study, a Kretschmann structure with a hybrid layer of graphene–WS2 is designed to develop a sensitive biosensor for deoxyribonucleic acid detection. The biosensor incorporates a 45 nm gold layer as the active layer and a thin film of chrome as the adhesive layer. Through the optimization of the graphene and WS2 layers, combined with the implementation of a silicon layer, we can enhance the nano-sensor’s sensitivity. The thin silicon layer acts as a protective barrier for the metal, while also increasing the volume of interaction. Consequently, by adjusting the thickness of the active metal and adding a silicon layer, we achieve higher sensitivity and a lower full width at half maximum, leading to sensitivity of 333.33°/RIU. The designed structure is analyzed using numerical techniques and the finite difference time domain method, allowing us to obtain the optical characteristics of the surface plasmon polariton sensor. Various parameters are calculated and evaluated to determine the optimal conditions for the sensor. Furthermore, the total size of the sensor is 2.228 µm2.
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来源期刊
Photonics
Photonics Physics and Astronomy-Instrumentation
CiteScore
2.60
自引率
20.80%
发文量
817
审稿时长
8 weeks
期刊介绍: Photonics (ISSN 2304-6732) aims at a fast turn around time for peer-reviewing manuscripts and producing accepted articles. The online-only and open access nature of the journal will allow for a speedy and wide circulation of your research as well as review articles. We aim at establishing Photonics as a leading venue for publishing high impact fundamental research but also applications of optics and photonics. The journal particularly welcomes both theoretical (simulation) and experimental research. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Electronic files and software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material.
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