2012 年至 2022 年期间北爱尔兰淋病传播的数学建模

Q4 Medicine Acta Microbiologica Hellenica Pub Date : 2024-06-06 DOI:10.3390/amh69020012
Gabor Kiss, Daniel Corken, Rebecca Hall, Alhassan Ibrahim, S. Moutari, Frank Kee, Gillian Armstrong, Declan Bradley, Maeve Middleton, Lynsey Patterson, Felicity Lamrock
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引用次数: 0

摘要

近来,英国各种性传播感染的确诊阳性检测数量有所增加。本研究旨在提出一个确定性分区模型,以调查 2012 年至 2022 年淋病在北爱尔兰的传播情况。基于微分方程的模型包括无症状和无症状传播、自发恢复和治疗区。在将模型拟合到每月新增阳性检测数量后,我们发现基本繁殖数约为 1.0030。此外,我们还推导出了该模型的地方性平衡,即只有当 R0>1 时才存在地方性平衡。对基本繁殖数和接受治疗的个体分区的流行值进行的敏感性分析表明,感染传播时间对淋病传播有重大影响。
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Mathematical Modelling of Gonorrhoea Spread in Northern Ireland between 2012 and 2022
The number of confirmed positive tests of various sexually transmitted infections has grown recently in the United Kingdom. The objective of this study is to propose a deterministic compartmental model to investigate gonorrhoea spread in Northern Ireland between 2012 and 2022. The differential equation based model includes both symptomatic and asymptomatic spread, spontaneous recovery and treatment compartments. After fitting our model to the monthly number of new positive tests, we found that the basic reproduction number is approximately 1.0030. In addition, we derive the endemic equilibrium of the model, which exists if and only if R0>1. The sensitivity analyses of the basic reproduction number and the endemic values of the compartments of treated individuals indicate that infection spreading time can have a significant impact on gonorrhoea spread.
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来源期刊
Acta Microbiologica Hellenica
Acta Microbiologica Hellenica Medicine-Microbiology (medical)
CiteScore
0.20
自引率
0.00%
发文量
6
期刊最新文献
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