炎症性肠病肠道超声的最新进展

Cathy Lu
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摘要

炎症性肠病(IBD)的治疗已从监测临床症状发展到利用内窥镜和放射成像对粘膜愈合情况进行客观测量。众所周知,临床症状与疾病严重程度并不相符。经常进行放射成像评估是目前的治疗标准。虽然《炎症性肠病治疗靶点选择》(STRIDE-II)建议并未将放射成像靶点列为终点,因为 "目前可用的治疗方法实现跨壁愈合的能力有限",但随着时间的推移,尤其是肠道超声(IUS)在临床试验中的应用迅速增加,这一点很可能会发生变化。目前,成像被认为是一种 "辅助评估,而不是正式的治疗目标"。
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Latest Intestinal Ultrasound Advancements In Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) treatment has evolved from monitoring clinical symptoms to targeting objective measurements of mucosal healing with endoscopic and radiologic imaging. It is well known that clinical symptoms do not match disease severity. Frequent evaluation with radiologic imaging is now the standard of care. Although Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE-II) recommendations do not list radiographic targets as an endpoint due to the “limited ability of the currently available treatments to achieve transmural healing,” this will likely evolve over time particularly with the rapidly growing uptake of intestinal ultrasound (IUS) in clinical trials. For the time being, imaging is considered as an “adjuvant assessment rather than a formal treatment target.”
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