A. Stefanis, Petr Arenberger, M. Arenbergerová, Dimitris Rigopoulos
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引用次数: 0
摘要
简介:雄激素性脱发(AGA)是最常见的脱发类型:雄激素性脱发(AGA)是最常见的脱发类型。富血小板血浆(PRP)和中胚层疗法(MZT)注射各种含有生长因子的溶液是治疗 AGA 的流行疗法。本研究旨在比较 RPP 和 MZT 产品治疗 AGA 的疗效。方法:这项回顾性研究包括 72 位接受两种 PRP 制剂和两种 MZT 产品治疗的 AGA 患者,他们均采用手动或枪式注射器进行注射。在治疗前和治疗后 6 个月测量了前额和头顶部位的毛发参数(毛发厚度、毛发密度和毛发数量)。结果显示在 6 个月内,毛发参数在组内和组间都有显著差异。MZT1 组和 PRP2 组在大多数参数上都有统计学意义上的显著改善,而 MZT2 组则显著增加了顶点毛发密度。PRP1 组和 PRP2 组之间的毛发厚度变化有明显差异(未调整的 p 值 <0.001),MZT1 组和 PRP1 组之间的毛发厚度变化也可能有差异(未调整的 p 值 = 0.049)。讨论注射 PRP 和 MZT 制剂可在 6 个月内显著改善 AGA 患者的三镜面参数,但不同 PRP 和 MZT 产品的改善程度各不相同。
Efficacy of Platelet-Rich Plasma versus Mesotherapy with Recombinant Growth Factors and Stem Cell-Conditioned Media in Androgenetic Alopecia: A Retrospective Study
Introduction: Androgenetic alopecia (AGA) is the most common type of hair loss. Platelet-rich plasma (PRP) and mesotherapy (MZT) injections of various solutions fortified with growth factors are popular treatment options for AGA. The aim of this study was to compare the efficacy of RPP and MZT products in the treatment of AGA. Methods: This retrospective study included 72 AGA patients treated with two PRP formulations and two MZT products, administered manually or with a gun injector. Hair parameters (hair thickness, hair density, and hair count) on frontal and vertex areas were measured before and after 6 months. Results: Over 6 months, trichoscopic parameters showed significant intragroup and intergroup variability. MZT1 and PRP2 groups exhibited statistically significant improvement in most parameters, while MZT2 significantly increased vertex hair density. Hair thickness changes differed significantly between PRP1 and PRP2 groups (unadjusted p value <0.001) and possibly between MZT1 and PRP1 groups (unadjusted p value = 0.049) in both regions. Discussion: Injections of PRP and MZT formulations can significantly enhance trichoscopic parameters in AGA patients within a 6-month period, but the extent of improvement varies among different PRP and MZT products.