产褥期妇女的神经性恶性综合征--夏季冰冻

IF 0.1 Q4 EMERGENCY MEDICINE Journal of Emergency Medicine Case Reports Pub Date : 2024-06-05 DOI:10.33706/jemcr.1420313
Sadesvaran Muniandy
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引用次数: 0

摘要

导言神经性恶性综合征是一种罕见病,在产褥期患者中更为罕见。发病风险为 0.11%。当患者长期服用抗精神病药物时,往往会出现这种情况。 病例报告 我们报告了一例女性患者,她在产后两周在家出现行为改变。入院前,她曾因产后精神病接受过抗精神病药物治疗。然而,由于她在病房时出现锥体外系症状,抗精神病药物被暂停使用。在家里,她出现了发烧、感觉改变和类似癫痫发作的症状。到达医院时,患者反应迟钝,呼吸道通畅性受损。她的生命体征不稳定,血压、心率和体温升高。脑部检查结果正常,排除了脑部病变。根据肌酸激酶升高的特征,她被诊断为神经性恶性综合征。对她进行了对症治疗,采取急救措施降低体温,并开始服用苯二氮卓类药物。结论 医生必须熟悉神经安定剂恶性综合征,并对其有高度的怀疑,以便识别和治疗。如不及时治疗,极易导致死亡。
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Neuroleptic malignant syndrome in puerperal women – frozen in summer
Introduction Neuroleptic malignant syndrome is an rare event, even more so among patient from puerperal period. The incidence risk is of 0.11%. It is often occurs when a patient is prescribed on antipsychotic for long duration of time. Case Report We report a case of a female patient, two weeks in post natal period presented with altered behaviour at home. She has prior admission being treated for post partum psychosis with anti psychotic. However antipschotic was withheld as she developed extrapyramidal symptoms while in ward. At home, she developed fever, altered sensorium and fitting-like-episode. On arrival patient was unresponsive and with features of impaired airway patency. Her had unstable vital sign with elevated blood pressure, heart rate and temperature. Brain imagine came back normal, excluding brain pathology. She was diagnosed as neuroleptic malignant syndrome as fulfilled features of elevated creatine kinase. She was treated symptomatic by providing first aid to reduce temperature and started on benzodiazepines. She was subsequently admitted to intensive ward and responded well to treatment Conclusion Physician must be familiar and have high index of suspicious to identify and treat neuroleptic malignant syndrome. Without prompt treatment, it is highly fatal.
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