D. A. Kasatov, Y. A. Kolesnikov, V. D. Konovalova, V. V. Porosev, E. O. Sokolova, I. M. Shchudlo, S. Y. Taskaev
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引用次数: 0
摘要
冷中子(能量为 10-7-10-4 eV)已在现代物理学的许多领域得到广泛应用。硼中子俘获治疗肿瘤疾病是低能中子的一个新的和有前景的应用领域。这种方法基于肿瘤中先前积累的硼-10的中子俘获,以及高能α粒子和锂原子核逸出后发生的10B(n,α)7Li反应。将冷中子直接输送到恶性肿瘤区域,可以增加肿瘤内治疗剂量的定位,排除对健康细胞的影响,并提高硼中子俘获疗法(BNСT)的有效性,无论是对深层恶性肿瘤还是表面恶性肿瘤都是如此。文章中描述的研究致力于在基于 VITA 加速器的表层中子源上产生冷中子。本文介绍了所设计的冷中子束整形组件(BSA)。介绍了使用 Geant4 软件对中子通过 BSA 进行的模拟。演示了在基于 VITA 加速器的表热中子源上产生冷中子的可能性。
Development of a System for Forming a Beam of Cold Neutrons for the VITA Accelerating Neutron Source
Cold neutrons (with energy 10–7–10–4 eV) have found broad application in many areas of modern physics. A new and prospective field of application of low-energy neutrons is the boron neutron capture therapy of oncological illness. This method is based on neutron capture by boron-10, previously accumulated in a tumor, and reaction 10B(n,α)7Li with following escape of energetic α particle and lithium atomic nucleus. The delivery of cold neutrons directly to the area of a malignant tumor can make it possible to increase the localization of the therapeutic dose in the tumor, exclude any impact on healthy cells, and increase the effectiveness of boron neutron capture therapy (BNСT), both in the case of deep-lying malignant tumors and those on the surface. The research described in the article is devoted to the generation of cold neutrons on the VITA accelerator-based epithermal neutron source. This paper describes the cold neutron beam shaping assembly (BSA) that has been designed. The simulation of neutron passage through the BSA performed using Geant4 software is described. The possibility of generating cold neutrons on the VITA accelerator-based epithermal neutron source was demonstrated.
期刊介绍:
The journal Physics of Particles and Nuclei Letters, brief name Particles and Nuclei Letters, publishes the articles with results of the original theoretical, experimental, scientific-technical, methodological and applied research. Subject matter of articles covers: theoretical physics, elementary particle physics, relativistic nuclear physics, nuclear physics and related problems in other branches of physics, neutron physics, condensed matter physics, physics and engineering at low temperatures, physics and engineering of accelerators, physical experimental instruments and methods, physical computation experiments, applied research in these branches of physics and radiology, ecology and nuclear medicine.