终末期肾病的手部感染--考虑肿瘤性钙化症

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引用次数: 0

摘要

肿瘤性钙化症(TC)是一种罕见的疾病,是指钙盐在关节(最常见的是大关节)周围的软组织中积聚。在局部高磷血症的情况下,慢性关节炎症会导致组织修复的中断和功能障碍,并产生随后钙化和积聚的分解产物。我们接诊了一例 42 岁的男性患者,他有终末期肾病透析史,因右手长指近端指间关节处出现无痛性数字肿块而就诊。根据患者的表现和病史,我们的初步印象是夹板脓肿。虽然我们的患者因终末期肾病继发手部创伤性无痛 TC 的病例非常罕见,但 TC 背后的致病机制支持这种病例。作者建议,在鉴别类似慢性脓肿或巨细胞瘤的表现时,应将手部创伤性无痛性脓肿包括在内,尤其是当病史中包括终末期肾病时。
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Hand Infections in End-Stage Renal Disease—Consider Tumoral Calcinosis

Tumoral calcinosis (TC) is a rare condition defined by the accumulation of calcium salts in soft tissues surrounding joints, most commonly large joints. Chronic joint inflammation in the setting of local hyperphosphatemia leads to interruption and dysfunction of tissue repair and generates breakdown products that subsequently calcify and accumulate. We present a case of a 42-year-old man with a history of end-stage renal disease on dialysis presenting to the clinic with a painless digital mass of his right long finger at the proximal interphalangeal joint. Our initial impression was a splinter abscess based on presentation and patient history. Although our patient’s presentation of traumatic, painless TC of the hand secondary to end-stage renal disease is rare, the pathogenic mechanisms behind TC support this presentation. The authors recommend including TC within the differential of presentations similar to that of chronic abscess or giant cell tumor, especially when their medical history includes end-stage renal disease.

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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
111
审稿时长
12 weeks
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