在培养皿中重现肿瘤微环境,一次只重现一种细胞类型。

IF 4.3 Q1 BIOCHEMICAL RESEARCH METHODS Cell Reports Methods Pub Date : 2024-06-17 DOI:10.1016/j.crmeth.2024.100800
Benjamin N Ostendorf
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引用次数: 0

摘要

肿瘤微环境中存在多种不同类型的细胞,它们对肿瘤生物学产生不同的影响。在本期《细胞报告方法》(Cell Reports Methods)杂志上,Raffo-Romero 等人对三维肿瘤器官组织进行了标准化和优化,以便在体外模拟肿瘤相关巨噬细胞和肿瘤细胞之间的相互作用。
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Recapitulating the tumor microenvironment in a dish, one cell type at a time.

The tumor microenvironment harbors a variety of different cell types that differentially impact tumor biology. In this issue of Cell Reports Methods, Raffo-Romero et al. standardized and optimized 3D tumor organoids to model the interactions between tumor-associated macrophages and tumor cells in vitro.

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来源期刊
Cell Reports Methods
Cell Reports Methods Chemistry (General), Biochemistry, Genetics and Molecular Biology (General), Immunology and Microbiology (General)
CiteScore
3.80
自引率
0.00%
发文量
0
审稿时长
111 days
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