胸骨正中切开术中胸骨旁周围神经导管与无阻滞的疗效对比:一项单中心回顾性研究

John E. Rubin , Vanessa Ng , Justin Chung , Nicolas Salvatierra , Brady Rippon , Diana Khatib , Natalia I. Girardi , Kane O. Pryor , Roniel Y. Weinberg , Silis Jiang , Sherif Khairallah , Stephanie L. Mick , Tiffany R. Tedore
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引用次数: 0

摘要

背景心脏手术后的胸骨疼痛会导致严重不适。有研究表明,单次注射胸骨旁筋膜面阻滞可降低术后 24 小时内的疼痛评分和阿片类药物消耗量,但连续输注的疗效尚未得到评估。这项回顾性队列研究探讨了通过胸骨旁导管持续输注局麻药对72小时内疼痛强度和阿片类药物消耗量(PIOC)综合评分的影响。方法我们对一家学术中心接受胸骨正中切开术的心脏手术患者在标准多模式镇痛方案中添加胸骨旁神经导管前后的情况进行了回顾性分析。结果与无阻滞相比,通过胸骨旁导管持续输注0.1%罗哌卡因可显著降低24小时(-62,95%置信区间-108至-16;P<0.01)和48小时(-50,95%置信区间-97至-2.2;P=0.04)的PIOC评分。结论这项研究表明,通过胸骨旁导管持续输注局麻药可能是胸骨切开术心脏手术患者多模式镇痛方案的有益补充。需要进一步开展前瞻性研究,以确定持续输注与单次注射或无阻滞相比的全部益处。
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Efficacy of parasternal peripheral nerve catheters versus no block for median sternotomy: a single-centre retrospective study

Background

Sternal pain after cardiac surgery results in considerable discomfort. Single-injection parasternal fascial plane blocks have been shown to reduce pain scores and opioid consumption during the first 24 h after surgery, but the efficacy of continuous infusion has not been evaluated. This retrospective cohort study examined the effect of a continuous infusion of local anaesthetic through parasternal catheters on the integrated Pain Intensity and Opioid Consumption (PIOC) score up to 72 h.

Methods

We performed a retrospective analysis of patients undergoing cardiac surgery with median sternotomy at a single academic centre before and after the addition of parasternal nerve catheters to a standard multimodal analgesic protocol. Outcomes included PIOC score, total opioid consumption in oral morphine equivalents, and time-weighted area under the curve pain scores up to 72 h after surgery.

Results

Continuous infusion of ropivacaine 0.1% through parasternal catheters resulted in a significant reduction in PIOC scores at 24 h (−62, 95% confidence interval −108 to −16; P<0.01) and 48 h (−50, 95% CI −97 to −2.2; P=0.04) compared with no block. A significant reduction in opioid consumption up to 72 h was the primary factor in reduction of PIOC.

Conclusions

This study suggests that continuous infusion of local anaesthetic through parasternal catheters may be a useful addition to a multimodal analgesic protocol in patients undergoing cardiac surgery with sternotomy. Further prospective study is warranted to determine the full benefits of continuous infusion compared with single injection or no block.

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来源期刊
BJA open
BJA open Anesthesiology and Pain Medicine
CiteScore
0.60
自引率
0.00%
发文量
0
审稿时长
83 days
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