高强度缝合线和胶带中双股绳结配置的生物力学评估。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-06-22 DOI:10.1007/s00068-024-02566-z
Mehar Dhillon, Tatjana Pastor, Ivan Zderic, Sarina Hebsacker, Björn-Christian Link, James Fletcher, R Geoff Richards, Boyko Gueorguiev, Torsten Pastor
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引用次数: 0

摘要

目的:最近推出了一种新型动态高强度缝合线 (DC),也有胶带形式 (DT),其特点是注入盐的硅胶芯在流体环境中吸水,以保持组织近似性。本研究的目的是:(1) 评估用动态(DC 和 DT)或传统(FW 和 ST)高强度缝合线和胶带打结的两种双股绳结配置(Cow-hitch 和 Nice-knot)的固定抛掷次数对绳结安全性的影响;(2) 比较新型动态缝合线和胶带与传统缝合线和胶带在使用所需的最小固定抛掷次数时的极限力和绳结滑动情况:方法:将 FW、ST、DC 和 DT 各 7 个试样考虑使用牛钩结或尼斯结进行打结。这些牛钩结和尼斯结的底部用外科医生结固定,交替使用 1-3 次。在生理条件下进行了拉伸试验,以评估绳结的滑动、断裂时的极限力以及确保绳结 100% 安全的最小抛掷次数。 结果:对于牛钩结和尼斯结而言,DC、DT 和 ST 用 2 次打结,FW 用 3 次打结,就能达到 100% 的安全性。在这些最低固定次数下,Nice-绳结的极限力明显高于用 DT 打结的 Cow-hitch(p = 0.001),Nice-绳结的滑动明显低于用 DC 打结的 Cow-hitch(p = 0.019):在 DC、DT 和 ST 中,牛绳和尼斯结都需要 2 次固定才能达到 100% 的安全性,而在 FW 中则需要 3 次固定。在使用这些最低固定次数的情况下,使用 DT 时,尼斯结的极限力明显更高,而使用 DC 时,滑移率则低于牛绳结。
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Biomechanical evaluation of double-stranded knot configurations in high-strength sutures and tapes.

Purpose: Recently, a new dynamic high-strength suture (DC) was introduced, also available in tape form (DT), featuring a salt-infused silicone core attracting water in a fluid environment to preserve tissue approximation. The aims of this study were to (1) assess the influence of securing throw number on knot security of two double-stranded knot configurations (Cow-hitch and Nice-knot) tied with either dynamic (DC and DT) or conventional (FW and ST) high-strength sutures and tapes, and (2) compare the ultimate force and knot slippage of the novel dynamic versus conventional sutures and tapes when used with their minimal number of needed securing throws.

Methods: Seven specimens of each FW, ST, DC and DT were considered for tying with Cow-hitch or Nice-knots. The base of these Cow-hitch and Nice-knots was secured with surgeons` knots using 1-3 alternating throws. Tensile tests were conducted under physiologic conditions to evaluate knot slippage, ultimate force at rupture, and minimum number of throws ensuring 100% knot security.  RESULTS:  For both Cow-hitch and Nice-knots, 100% security was achieved with 2 securing throws for DC, DT, ST, and with 3 securing throws for FW. With these minimum numbers of securing throws, ultimate force was significantly higher for Nice-knots versus Cow-hitch tied with DT (p = 0.001) and slippage was significantly less with Nice-knots versus Cow-hitch tied with DC (p = 0.019).

Conclusions: The minimum number of securing throws required to achieve 100% security was 2 with DC, DT and ST for both Cow-hitch and Nice-knots configurations, in contrast to FW where 3 securing throws were needed. With these minimum numbers of securing throws, Nice-knots were associated with significantly higher ultimate forces when using DT and lower slippage with DC versus Cow-hitch knots.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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