黑色素瘤的微生物组和免疫疗法:我们准备好临床应用了吗?

IF 2.5 3区 医学 Q2 HEMATOLOGY Hematology-Oncology Clinics of North America Pub Date : 2024-06-21 DOI:10.1016/j.hoc.2024.05.010
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引用次数: 0

摘要

微生物组对转移性黑色素瘤患者接受免疫检查点阻断疗法(ICB)的疗效起着重要作用。虽然肠道微生物组的确切组成和参与这种相互作用的途径尚未明确界定,但新的研究和正在进行的临床试验很可能会揭示出适用于临床环境的结果,以预测和优化对 ICB 的反应。不过,调整生活方式,包括高纤维饮食、避免不必要的抗生素处方以及谨慎使用益生菌,可能有助于优化肠道微生物组的 "健康",并有可能增强黑色素瘤患者对 ICB 的反应。
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Microbiome and Immunotherapy for Melanoma
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来源期刊
CiteScore
4.10
自引率
0.00%
发文量
86
审稿时长
6-12 weeks
期刊介绍: Hematology/Oncology Clinics updates you on the latest trends in patient management, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Under the direction of an experienced guest editor, each issue focuses on a single topic in hematology and oncology, including hemostasis and thrombosis, molecular and cellular basis of hematology, coagulation disorders, and cancers—bone, gastrointestinal, head and neck, lymphomas, neuroendocrine, breast, renal cell, melanoma, and more.
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