了解 "Atmosome"(个人大气暴露体):综合方法。

Hari Bhimaraju, Nitish Nag, Vaibhav Pandey, Ramesh Jain
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引用次数: 0

摘要

背景:现代环境健康研究广泛关注室外空气污染物及其对公众健康的影响。然而,有关监测和提高个人室内空气质量的研究却十分缺乏。暴露组学领域涵盖了人类环境暴露的全部内容及其对健康的影响。暴露组的一个子集涉及大气暴露,称为 "大气组"。大气组对健康起着关键作用,对 DNA、新陈代谢、皮肤完整性和肺部健康有重大影响:这项工作的目的是开发一种低成本的综合测量系统,用于收集和分析大气组因素。研究探讨了大气组在公共卫生的个性化和预防性护理中的意义:方法:介绍并演示了一个基于微控制器的物联网系统。方法:介绍并演示了一个基于物联网微控制器的系统,该系统实时收集室内空气质量数据,并发布到云端供即时访问:实验结果:与预先校准的商用设备相比,空气质量测量的准确率达到 90%,并证明了生活方式与空气质量之间的直接相关性:量化个人空气质量是推进个性化健康、医学研究和流行病学研究的重要一步。这项工作的两个主要目标是提出大气组这一可测量的概念,并展示如何利用低成本电子设备实现这一概念。通过在社区范围内实现大气组测量,这项工作还为公共卫生研究开辟了潜在的新方向。研究人员现在将有数据来模拟室内空气污染物对个人、社区和特定人群健康的影响,从而找到预测和预防疾病的新方法。
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Understanding "Atmosome", the Personal Atmospheric Exposome: Comprehensive Approach.

Background: Modern environmental health research extensively focuses on outdoor air pollutants and their effects on public health. However, research on monitoring and enhancing individual indoor air quality is lacking. The field of exposomics encompasses the totality of human environmental exposures and its effects on health. A subset of this exposome deals with atmospheric exposure, termed the "atmosome." The atmosome plays a pivotal role in health and has significant effects on DNA, metabolism, skin integrity, and lung health.

Objective: The aim of this work is to develop a low-cost, comprehensive measurement system for collecting and analyzing atmosomic factors. The research explores the significance of the atmosome in personalized and preventive care for public health.

Methods: An internet of things microcontroller-based system is introduced and demonstrated. The system collects real-time indoor air quality data and posts it to the cloud for immediate access.

Results: The experimental results yield air quality measurements with an accuracy of 90% when compared with precalibrated commercial devices and demonstrate a direct correlation between lifestyle and air quality.

Conclusions: Quantifying the individual atmosome is a monumental step in advancing personalized health, medical research, and epidemiological research. The 2 main goals in this work are to present the atmosome as a measurable concept and to demonstrate how to implement it using low-cost electronics. By enabling atmosome measurements at a communal scale, this work also opens up potential new directions for public health research. Researchers will now have the data to model the impact of indoor air pollutants on the health of individuals, communities, and specific demographics, leading to novel approaches for predicting and preventing diseases.

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