大麻二酚在牛皮癣治疗中的应用前景。

IF 5.2 Q1 DERMATOLOGY Psoriasis (Auckland, N.Z.) Pub Date : 2024-06-19 eCollection Date: 2024-01-01 DOI:10.2147/PTT.S469698
Ana Maria Alexandra Stanescu, Gabriel Cristian Bejan, Mihaela Daniela Balta, Octavian Andronic, Cristian Toma, Stefan Busnatu
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引用次数: 0

摘要

银屑病是一种慢性皮肤病,会严重影响患者的生活质量。作为一种自身免疫性疾病,它会导致皮肤出现瘙痒、疼痛和鳞屑斑块。虽然目前有各种治疗方法,包括外用药膏、光疗和全身用药,但这些方法并不总能有效缓解病情,而且可能会产生副作用。因此,研究人员一直在探索非精神活性化合物(如大麻中的 CBD)治疗牛皮癣的潜在益处。CBD 治疗可减少炎症、氧化应激、瘙痒、角质细胞异常增殖,并可增加水合作用。本综述旨在概述有关 CBD 治疗银屑病潜在用途的现有文献。
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The Perspective of Cannabidiol in Psoriasis Therapy.

Psoriasis is a chronic skin condition that can significantly impact the quality of life of those affected. As an autoimmune disease, it can lead to itchy, painful, and scaly patches on the skin. Although various treatments, including topical creams, phototherapy, and systemic medications, are currently available, they may not always offer effective relief and can have side effects. Researchers have thus been exploring the potential benefits of non-psychoactive compounds such as CBD, found in Cannabis sativa plants, for treating psoriasis. CBD treatment may reduce inflammation, oxidative stress, itching, abnormal proliferation of keratinocytes, and may increase hydration. This review aims to provide an overview of the existing literature on the potential uses of CBD for psoriasis treatment.

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