{"title":"使用 CuCF2CF3 对苯乙烯衍生物进行歧化五氟乙烷化反应","authors":"Zhengjie Fu and Gavin Chit Tsui","doi":"10.1039/D4QO00768A","DOIUrl":null,"url":null,"abstract":"<p >A series of pentafluoroethylation reactions of styrene derivatives are described using the [CuCF<small><sub>2</sub></small>CF<small><sub>3</sub></small>] reagent prepared from low-cost pentafluoroethane (HCF<small><sub>2</sub></small>CF<small><sub>3</sub></small>). Under aerobic conditions, chloropentafluoroethylation, dimerization-pentafluoroethylation, vinylic pentafluoroethylation, formyloxylation-pentafluoroethylation and hydroxypentafluoroethylation can be achieved using styrenes to generate various functionalized products containing the CF<small><sub>2</sub></small>CF<small><sub>3</sub></small> group. It is remarkable that a single reagent is capable of such divergent reactivities with readily available feedstocks.</p>","PeriodicalId":97,"journal":{"name":"Organic Chemistry Frontiers","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Divergent pentafluoroethylation of styrene derivatives using CuCF2CF3†\",\"authors\":\"Zhengjie Fu and Gavin Chit Tsui\",\"doi\":\"10.1039/D4QO00768A\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p >A series of pentafluoroethylation reactions of styrene derivatives are described using the [CuCF<small><sub>2</sub></small>CF<small><sub>3</sub></small>] reagent prepared from low-cost pentafluoroethane (HCF<small><sub>2</sub></small>CF<small><sub>3</sub></small>). Under aerobic conditions, chloropentafluoroethylation, dimerization-pentafluoroethylation, vinylic pentafluoroethylation, formyloxylation-pentafluoroethylation and hydroxypentafluoroethylation can be achieved using styrenes to generate various functionalized products containing the CF<small><sub>2</sub></small>CF<small><sub>3</sub></small> group. It is remarkable that a single reagent is capable of such divergent reactivities with readily available feedstocks.</p>\",\"PeriodicalId\":97,\"journal\":{\"name\":\"Organic Chemistry Frontiers\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.6000,\"publicationDate\":\"2024-06-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Organic Chemistry Frontiers\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://pubs.rsc.org/en/content/articlelanding/2024/qo/d4qo00768a\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic Chemistry Frontiers","FirstCategoryId":"92","ListUrlMain":"https://pubs.rsc.org/en/content/articlelanding/2024/qo/d4qo00768a","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
Divergent pentafluoroethylation of styrene derivatives using CuCF2CF3†
A series of pentafluoroethylation reactions of styrene derivatives are described using the [CuCF2CF3] reagent prepared from low-cost pentafluoroethane (HCF2CF3). Under aerobic conditions, chloropentafluoroethylation, dimerization-pentafluoroethylation, vinylic pentafluoroethylation, formyloxylation-pentafluoroethylation and hydroxypentafluoroethylation can be achieved using styrenes to generate various functionalized products containing the CF2CF3 group. It is remarkable that a single reagent is capable of such divergent reactivities with readily available feedstocks.
期刊介绍:
Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.