利用光谱 CT 衍生虚拟单能成像评估冠状动脉的窗口设置优化。

IF 9.7 1区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Radiologia Medica Pub Date : 2024-07-01 Epub Date: 2024-06-27 DOI:10.1007/s11547-024-01835-6
Tommaso D'Angelo, Domenico Mastrodicasa, Ludovica R M Lanzafame, Ibrahim Yel, Vitali Koch, Leon D Gruenewald, Simran P Sharma, Velio Ascenti, Antonino Micari, Alfredo Blandino, Thomas J Vogl, Silvio Mazziotti, Ricardo P J Budde, Christian Booz
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引用次数: 0

摘要

目的:确定从双层频谱冠状动脉计算机断层扫描(DE-CCTA)数据集重建的虚拟单能图像(VMI)的最佳窗口设置。材料和方法:回顾性纳入 2021 年 5 月至 2022 年 6 月期间因疑似冠状动脉疾病接受 DE-CCTA 的 50 名患者(30 名男性;平均年龄 61.1 ± 12.4 岁)。对常规图像和 70 和 40 千伏的 VMI 重建进行了图像质量评估。客观图像质量采用对比-噪声比(CNR)进行评估。两名独立观察员手动确定 VMI 70 和 VMI 40 可视化的最佳窗口设置(B-W/L)。然后使用线性回归分析将 B-W/L 与主动脉衰减归一化,以获得最佳 W/L 设置(O-W/L)。此外,还使用 5 点李克特量表评估了主观图像质量,并测量了血管直径,以检查不同 W/L 设置的潜在影响:结果:与常规和 VMI 70 相比,VMI 40 显示出更高的 CNR 值。VMI 70 的 B-W/L 设置为 1180/280 HU,VMI 40 为 3290/900 HU。随后的线性回归分析得出,VMI 70 的 O-W/L 设置为 1155/270 HU,VMI 40 为 3230/880 HU。与常规相比,VMI 40 的 O-W/L 各项参数得分最高(所有 p 均为结论):优化 VMI 需要调整 W/L 设置。我们的结果建议 VMI 70 的 W/L 设置为 1155/270 HU,VMI 40 的 W/L 设置为 3230/880 HU。
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Optimization of window settings for coronary arteries assessment using spectral CT-derived virtual monoenergetic imaging.

Purpose: To determine the optimal window setting for virtual monoenergetic images (VMI) reconstructed from dual-layer spectral coronary computed tomography angiography (DE-CCTA) datasets.

Material and methods: 50 patients (30 males; mean age 61.1 ± 12.4 years who underwent DE-CCTA from May 2021 to June 2022 for suspected coronary artery disease, were retrospectively included. Image quality assessment was performed on conventional images and VMI reconstructions at 70 and 40 keV. Objective image quality was assessed using contrast-to-noise ratio (CNR). Two independent observers manually identified the best window settings (B-W/L) for VMI 70 and VMI 40 visualization. B-W/L were then normalized with aortic attenuation using linear regression analysis to obtain the optimized W/L (O-W/L) settings. Additionally, subjective image quality was evaluated using a 5-point Likert scale, and vessel diameters were measured to examine any potential impact of different W/L settings.

Results: VMI 40 demonstrated higher CNR values compared to conventional and VMI 70. B-W/L settings identified were 1180/280 HU for VMI 70 and 3290/900 HU for VMI 40. Subsequent linear regression analysis yielded O-W/L settings of 1155/270 HU for VMI 70 and 3230/880 HU for VMI 40. VMI 40 O-W/L received the highest scores for each parameter compared to conventional (all p < 0.0027). Using O-W/L settings for VMI 70 and VMI 40 did not result in significant differences in vessel measurements compared to conventional images.

Conclusion: Optimization of VMI requires adjustments in W/L settings. Our results recommend W/L settings of 1155/270 HU for VMI 70 and 3230/880 HU for VMI 40.

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来源期刊
Radiologia Medica
Radiologia Medica 医学-核医学
CiteScore
14.10
自引率
7.90%
发文量
133
审稿时长
4-8 weeks
期刊介绍: Felice Perussia founded La radiologia medica in 1914. It is a peer-reviewed journal and serves as the official journal of the Italian Society of Medical and Interventional Radiology (SIRM). The primary purpose of the journal is to disseminate information related to Radiology, especially advancements in diagnostic imaging and related disciplines. La radiologia medica welcomes original research on both fundamental and clinical aspects of modern radiology, with a particular focus on diagnostic and interventional imaging techniques. It also covers topics such as radiotherapy, nuclear medicine, radiobiology, health physics, and artificial intelligence in the context of clinical implications. The journal includes various types of contributions such as original articles, review articles, editorials, short reports, and letters to the editor. With an esteemed Editorial Board and a selection of insightful reports, the journal is an indispensable resource for radiologists and professionals in related fields. Ultimately, La radiologia medica aims to serve as a platform for international collaboration and knowledge sharing within the radiological community.
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