在不同温度下进行游泳训练并补充肉桂对糖尿病大鼠肝酶和甲状腺激素的影响

IF 1.9 Q3 CHEMISTRY, MEDICINAL Avicenna Journal of Phytomedicine Pub Date : 2024-01-01 DOI:10.22038/AJP.2023.23248
Sepehr Arammi, Massoud Sahragard, Asiye Seyed, Omidreza Salehi, Seyed Ali Hosseini, Zahra Mosallanezhad
{"title":"在不同温度下进行游泳训练并补充肉桂对糖尿病大鼠肝酶和甲状腺激素的影响","authors":"Sepehr Arammi, Massoud Sahragard, Asiye Seyed, Omidreza Salehi, Seyed Ali Hosseini, Zahra Mosallanezhad","doi":"10.22038/AJP.2023.23248","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to investigate the effects of swimming (S) training in water at 5°C (S5C) and 35°C (S35C) along with cinnamon (Cin) supplementationon liver enzymes and thyroid hormones in streptozotocin (STZ(-induced diabetic rats.</p><p><strong>Materials and methods: </strong>In this experimental trial, 48 diabetic rats (55 mg/kg STZ) were divided into (1) diabetic control (CD), (2) S5C, (3) S5C+Cin, (4) S35C, (5) S35C+Cin and (6) Cin groups.Eight rats were placed in the healthy control (HC) group to evaluate the effects of diabetes induction on the research variables. Swimming training was performed at 5±2°C and 35±2°C for eight weeks, 3 days a week.For Cin supplementation, 200 mg/kg/day of the aqueous extract of cinnamon was dissolved in the animals drinking water. One-way analysis of variance with Tukey's <i>post- hoc</i> test in Graphpad Prism software was used to analyze the findings.</p><p><strong>Results: </strong>S5C and S35C significantly increased thyroid-stimulating hormone (TSH), and decreased alkaline phosphatase (ALP) and alanine aminotransferase <b>(</b>ALT)(p≤0.05). TSH levels in the S35C group were higher than the S5C group (p≥0.05); ALT levels in the S5C group were lower than the S35C group (p≥0.05). Also, Cin decreased AST and ALT levels (p≥0.05), while S35C+Cin decreased T3, ALP and ALT and S5C+Cin decreased ALP (p≥0.05).</p><p><strong>Conclusion: </strong>It seems that training at different temperatures and consumption of cinnamon synergistically lead to improvement of liver enzymes and modulation of thyroid hormones. However, the effect of training in cold water and its impact on thyroid hormones is still unknown and needs further research.</p>","PeriodicalId":8677,"journal":{"name":"Avicenna Journal of Phytomedicine","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11210701/pdf/","citationCount":"0","resultStr":"{\"title\":\"The effects of swimming training at different temperatures along with cinnamon supplementation on liver enzymes and thyroid hormones in diabetic rats.\",\"authors\":\"Sepehr Arammi, Massoud Sahragard, Asiye Seyed, Omidreza Salehi, Seyed Ali Hosseini, Zahra Mosallanezhad\",\"doi\":\"10.22038/AJP.2023.23248\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>The aim of this study was to investigate the effects of swimming (S) training in water at 5°C (S5C) and 35°C (S35C) along with cinnamon (Cin) supplementationon liver enzymes and thyroid hormones in streptozotocin (STZ(-induced diabetic rats.</p><p><strong>Materials and methods: </strong>In this experimental trial, 48 diabetic rats (55 mg/kg STZ) were divided into (1) diabetic control (CD), (2) S5C, (3) S5C+Cin, (4) S35C, (5) S35C+Cin and (6) Cin groups.Eight rats were placed in the healthy control (HC) group to evaluate the effects of diabetes induction on the research variables. Swimming training was performed at 5±2°C and 35±2°C for eight weeks, 3 days a week.For Cin supplementation, 200 mg/kg/day of the aqueous extract of cinnamon was dissolved in the animals drinking water. One-way analysis of variance with Tukey's <i>post- hoc</i> test in Graphpad Prism software was used to analyze the findings.</p><p><strong>Results: </strong>S5C and S35C significantly increased thyroid-stimulating hormone (TSH), and decreased alkaline phosphatase (ALP) and alanine aminotransferase <b>(</b>ALT)(p≤0.05). TSH levels in the S35C group were higher than the S5C group (p≥0.05); ALT levels in the S5C group were lower than the S35C group (p≥0.05). Also, Cin decreased AST and ALT levels (p≥0.05), while S35C+Cin decreased T3, ALP and ALT and S5C+Cin decreased ALP (p≥0.05).</p><p><strong>Conclusion: </strong>It seems that training at different temperatures and consumption of cinnamon synergistically lead to improvement of liver enzymes and modulation of thyroid hormones. However, the effect of training in cold water and its impact on thyroid hormones is still unknown and needs further research.</p>\",\"PeriodicalId\":8677,\"journal\":{\"name\":\"Avicenna Journal of Phytomedicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11210701/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Avicenna Journal of Phytomedicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22038/AJP.2023.23248\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, MEDICINAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Avicenna Journal of Phytomedicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22038/AJP.2023.23248","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
引用次数: 0

摘要

研究目的本研究旨在探讨在5°C(S5C)和35°C(S35C)水中进行游泳(S)训练并补充肉桂(Cin)对链脲佐菌素(STZ)诱导的糖尿病大鼠肝酶和甲状腺激素的影响:本实验将 48 只糖尿病大鼠(55 mg/kg STZ)分为(1) 糖尿病对照组 (CD)、(2) S5C 组、(3) S5C+Cin 组、(4) S35C 组、(5) S35C+Cin 组和 (6) Cin 组。在5±2°C和35±2°C条件下进行游泳训练,为期8周,每周3天。使用 Graphpad Prism 软件中的单因素方差分析和 Tukey 后检验分析结果:结果:S5C和S35C能明显增加促甲状腺激素(TSH),降低碱性磷酸酶(ALP)和丙氨酸氨基转移酶(ALT)(p≤0.05)。S35C组的TSH水平高于S5C组(P≥0.05);S5C组的ALT水平低于S35C组(P≥0.05)。此外,Cin 降低了 AST 和 ALT 水平(p≥0.05),而 S35C+Cin 降低了 T3、ALP 和 ALT,S5C+Cin 降低了 ALP(p≥0.05):不同温度下的训练和食用肉桂似乎能协同改善肝酶和调节甲状腺激素。然而,在冷水中训练的效果及其对甲状腺激素的影响仍是未知数,需要进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
The effects of swimming training at different temperatures along with cinnamon supplementation on liver enzymes and thyroid hormones in diabetic rats.

Objective: The aim of this study was to investigate the effects of swimming (S) training in water at 5°C (S5C) and 35°C (S35C) along with cinnamon (Cin) supplementationon liver enzymes and thyroid hormones in streptozotocin (STZ(-induced diabetic rats.

Materials and methods: In this experimental trial, 48 diabetic rats (55 mg/kg STZ) were divided into (1) diabetic control (CD), (2) S5C, (3) S5C+Cin, (4) S35C, (5) S35C+Cin and (6) Cin groups.Eight rats were placed in the healthy control (HC) group to evaluate the effects of diabetes induction on the research variables. Swimming training was performed at 5±2°C and 35±2°C for eight weeks, 3 days a week.For Cin supplementation, 200 mg/kg/day of the aqueous extract of cinnamon was dissolved in the animals drinking water. One-way analysis of variance with Tukey's post- hoc test in Graphpad Prism software was used to analyze the findings.

Results: S5C and S35C significantly increased thyroid-stimulating hormone (TSH), and decreased alkaline phosphatase (ALP) and alanine aminotransferase (ALT)(p≤0.05). TSH levels in the S35C group were higher than the S5C group (p≥0.05); ALT levels in the S5C group were lower than the S35C group (p≥0.05). Also, Cin decreased AST and ALT levels (p≥0.05), while S35C+Cin decreased T3, ALP and ALT and S5C+Cin decreased ALP (p≥0.05).

Conclusion: It seems that training at different temperatures and consumption of cinnamon synergistically lead to improvement of liver enzymes and modulation of thyroid hormones. However, the effect of training in cold water and its impact on thyroid hormones is still unknown and needs further research.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Avicenna Journal of Phytomedicine
Avicenna Journal of Phytomedicine CHEMISTRY, MEDICINAL-
CiteScore
3.40
自引率
4.50%
发文量
17
审稿时长
6 weeks
期刊最新文献
Aloe vera supplementation improves cardiovascular risk factors in hemodialysis patients: A randomized, double-blind, placebo-controlled trial. An in vitro antiviral evaluation of punicalagin toward influenza A virus. Apigenin attenuates serum concentrations of TNF-a, interleukin 1b and interleukin 6 in lipopolysaccharide-stimulated rats. Comparison of effects of P-coumaric acid and coumarin on colorectal cancer cell line by inducing apoptosis and autophagy. Effect of pretreatment with Devil's Claw on locomotor activity, infarct volume, and neuronal density in focal cerebral ischemia in rats.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1