吻肽（Kisspeptin）1 合成类似物影响下丹利鱼体内皮质醇水平的动态变化。

Q3 Biochemistry, Genetics and Molecular Biology Biomeditsinskaya khimiya Pub Date : 2024-06-01 DOI:10.18097/PBMC20247003176

A A Nuzhnova, M I Kostina, A A Blazhenko

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引用次数: 0

摘要

我们研究了参与调节下丘脑-垂体-性腺（HPG）应激轴的一种肽--基斯肽 1 的合成类似物对丹顶鹤皮质醇水平的影响。我们发现，剂量为 2 μg/kg 和 8 μg/kg 的吻肽会增加皮质醇水平，注射后 1 小时皮质醇水平显著飙升。

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Dynamics in cortisol levels in Danio rerio fish under the influence of a synthetic analog of kisspeptin 1.

The effect of a synthetic analog of kisspeptin 1, a peptide involved in the regulation of the hypothalamicpituitary- gonadal (HPG) stress axis, on the cortisol level of Danio rerio fish was investigated. Kisspeptin 1 was administered at doses of 2 μg/kg and 8 μg/kg followed by resting for 1 h and 4 h. We found that kisspeptin at doses of 2 μg/kg and 8 μg/kg increased cortisol levels, with a significant spike in cortisol levels at 1 h post-injection.

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来源期刊

Biomeditsinskaya khimiya Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

1.30

自引率

0.00%

发文量

期刊介绍： The aim of the Russian-language journal "Biomeditsinskaya Khimiya" (Biomedical Chemistry) is to introduce the latest results obtained by scientists from Russia and other Republics of the Former Soviet Union. The Journal will cover all major areas of Biomedical chemistry, including neurochemistry, clinical chemistry, molecular biology of pathological processes, gene therapy, development of new drugs and their biochemical pharmacology, introduction and advertisement of new (biochemical) methods into experimental and clinical medicine etc. The Journal also publish review articles. All issues of journal usually contain invited reviews. Papers written in Russian contain abstract (in English).